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Infertility; Early Menopause And Infertility In Females After Treatment For Childhood Cancer", "flags": [ "Updated \u226430d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06552091", "url": "https://clinicaltrials.gov/study/NCT06552091", "title": "Guided Digital Self-Hypnosis Solution for Managing Hot Flashes in Patients Undergoing Adjuvant Hormone Therapy", "sponsor": "Institut de Canc\u00e9rologie de Lorraine", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-12-20", "primary_completion": "2027-09-20 (est.)", "enrollment": 76, "enrollment_type": "Estimated", "countries": [ "France" ], "sex": "Female", "last_update": "2026-10-02", "first_posted": "2024-08-13", "results_posted": "", "conditions": "Breast Cancer Female", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT05571514", "url": "https://clinicaltrials.gov/study/NCT05571514", "title": "Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis", "sponsor": "Centre Hospitalier Universitaire de Saint Etienne", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-05-12", "primary_completion": "2027-11 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [ "France" ], "sex": "Female", "last_update": "2026-10-02", "first_posted": "2022-10-07", "results_posted": "", "conditions": "Post Menopausal Osteoporosis", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07663305", "url": "https://clinicaltrials.gov/study/NCT07663305", "title": "Evaluation of a Mobile Menopause Application", "sponsor": "Endo Health GmbH", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-07-06", "primary_completion": "2027-05 (est.)", "enrollment": 426, "enrollment_type": "Estimated", "countries": [ "Germany" ], "sex": "Female", "last_update": "2026-10-02", "first_posted": "2026-06-23", "results_posted": "", "conditions": "N95.1 Menopausal and Female Climacteric States", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06798571", "url": "https://clinicaltrials.gov/study/NCT06798571", "title": "Role of Menopause in Thermoregulation", "sponsor": "Penn State University", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-03-01", "primary_completion": "2026-12-01 (est.)", "enrollment": 24, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-10-02", "first_posted": "2025-01-29", "results_posted": "", "conditions": "Menopause; Aging", "flags": [ "Updated \u226430d" ], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07672002", "url": "https://clinicaltrials.gov/study/NCT07672002", "title": "Cuidar-ME, a Web-based Psychological Intervention for (Peri)Menopausal Women: A Pilot Randomized Controlled Trial", "sponsor": "University of Coimbra", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "ACTIVE_NOT_RECRUITING", "status": "Active, not recruiting", "open": false, "start": "2026-09-01", "primary_completion": "2027-02-01 (est.)", "enrollment": 150, "enrollment_type": "Estimated", "countries": [ "Portugal" ], "sex": "Female", "last_update": "2026-10-01", "first_posted": "2026-06-26", "results_posted": "", "conditions": "Menopause; Perimenopause", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07005648", "url": "https://clinicaltrials.gov/study/NCT07005648", "title": "Brazilian Registry of Menopausal Health", "sponsor": "Science Valley Research Institute", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-09-11", "primary_completion": "2027-09-11 (est.)", "enrollment": 1592, "enrollment_type": "Estimated", "countries": [ "Brazil" ], "sex": "All", "last_update": "2026-10-01", "first_posted": "2025-06-05", "results_posted": "", "conditions": "Menopause", "flags": [ "Updated \u226430d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07851662", "url": "https://clinicaltrials.gov/study/NCT07851662", "title": "Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes", "sponsor": "Institut de Recherches Cliniques de Montreal", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-12 (est.)", "primary_completion": "2030-09 (est.)", "enrollment": 63, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2026-10-01", "first_posted": "2026-10-01", "results_posted": "", "conditions": "Type 1 Diabetes (T1D); Menopause", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "EU CTIS", "id": "2026-525569-30-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2026-525569-30-00", "title": "A study to learn how a high-fat meal affects the way elinzanetant is taken up by the body in healthy women", "sponsor": "Bayer AG", "sponsor_class": "Pharmaceutical company", "phase": "Human Pharmacology (Phase I)- Other", "study_type": "Interventional", "status_code": 5, "status": "Ongoing, recruitment ended", "open": false, "start": "2026-09-08", "primary_completion": "", "enrollment": "30", "enrollment_type": "Planned", "countries": [ "Germany" ], "sex": "Female", "last_update": "2026-10-01", "first_posted": "2026-07-10", "results_posted": "", "conditions": "Vasomotor symptoms as a sex hormone-dependent disorder in women and men", "flags": [ "Updated \u226430d" ], "phase_group": "Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT07848438", "url": "https://clinicaltrials.gov/study/NCT07848438", "title": "Sex Hormones and Aging", "sponsor": "University of Michigan", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-08-20", "primary_completion": "2031-08 (est.)", "enrollment": 120, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-30", "first_posted": "2026-09-30", "results_posted": "", "conditions": "Menopause; Menopausal Hormone Therapy; Aging", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07850167", "url": "https://clinicaltrials.gov/study/NCT07850167", "title": "Menstrual Cycle, Menopause, and Pain Perception During Endodontic Treatment", "sponsor": "Nigde Omer Halisdemir University", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-10", "primary_completion": "2027-03 (est.)", "enrollment": 130, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-09-30", "first_posted": "2026-09-30", "results_posted": "", "conditions": "Pain Perception in Endodontic Treatment; Menstrual Cycle; Menopause", "flags": [ "New", "Updated \u226430d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07408440", "url": "https://clinicaltrials.gov/study/NCT07408440", "title": "Transdermal Testosterone Gel for Female Sexual Interest and Arousal Disorder in Peri- and Post Menopause", "sponsor": "The University of Texas Health Science Center, Houston", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2027-01-01 (est.)", "primary_completion": "2028-03-30 (est.)", "enrollment": 150, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-29", "first_posted": "2026-02-13", "results_posted": "", "conditions": "Menopause; Sexual Dysfunction; Libido Disorder; Testosterone Deficiency", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07688720", "url": "https://clinicaltrials.gov/study/NCT07688720", "title": "Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause", "sponsor": "Texas Christian University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-10 (est.)", "primary_completion": "2027-03 (est.)", "enrollment": 20, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-29", "first_posted": "2026-07-07", "results_posted": "", "conditions": "Perimenopause; PMDD", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07822230", "url": "https://clinicaltrials.gov/study/NCT07822230", "title": "Effects of a Dietary Intervention Based on the Dietary Guidelines for the Brazilian Population on the Reduction of Menopausal Symptoms in Overweight and Obese Women", "sponsor": "Federal University of Health Science of Porto Alegre", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-05-06", "primary_completion": "2027-07-30 (est.)", "enrollment": 74, "enrollment_type": "Estimated", "countries": [ "Brazil" ], "sex": "Female", "last_update": "2026-09-29", "first_posted": "2026-09-16", "results_posted": "", "conditions": "Menopause; Menopause Hot Flashes; Overweight , Obesity; Perimenopause, Climacteric Syndrome; Postmenopause; Menopause-related Hot Flashes; Menopause Related Conditions; Menopause Symptoms; Climactericum", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07829653", "url": "https://clinicaltrials.gov/study/NCT07829653", "title": "A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause", "sponsor": "Astellas Pharma Inc", "sponsor_class": "INDUSTRY", "phase": "Phase 3", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-31 (est.)", "primary_completion": "2028-03-31 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-09-28", "first_posted": "2026-09-21", "results_posted": "", "conditions": "Hot Flashes", "flags": [ "New", "Updated \u226430d" ], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06673199", "url": "https://clinicaltrials.gov/study/NCT06673199", "title": "The Influence of the \"Washoku\" Diet on the Gut Microbiota in Postmenopausal Women", "sponsor": "Joanna Bajerska", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2024-11-16", "primary_completion": "2025-05-31", "enrollment": 35, "enrollment_type": "Actual", "countries": [ "Poland" ], "sex": "Female", "last_update": "2026-09-28", "first_posted": "2024-11-04", "results_posted": "", "conditions": "Menopause", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07842614", "url": "https://clinicaltrials.gov/study/NCT07842614", "title": "Effect of a Brassicaceae-Enriched Diet on Menopausal Symptoms in Women With Breast Cancer Receiving Antiestrogen Therapy", "sponsor": "Azienda Ospedaliero, Universitaria Pisana", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2020-10-30", "primary_completion": "2024-10-01", "enrollment": 81, "enrollment_type": "Actual", "countries": [ "Italy" ], "sex": "Female", "last_update": "2026-09-25", "first_posted": "2026-09-25", "results_posted": "", "conditions": "Breast Cancer; Menopausal Symptoms", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07633743", "url": "https://clinicaltrials.gov/study/NCT07633743", "title": "MenoZen VR for Menopause Symptom Management", "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-09-28 (est.)", "primary_completion": "2027-07-31 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-24", "first_posted": "2026-06-08", "results_posted": "", "conditions": "Menopause", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07839299", "url": "https://clinicaltrials.gov/study/NCT07839299", "title": "Bonafide Sleep Supplement for Menopausal Women With Impaired Sleep", "sponsor": "Bonafide Health", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-01-03", "primary_completion": "2025-08-23", "enrollment": 90, "enrollment_type": "Actual", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-24", "first_posted": "2026-09-24", "results_posted": "", "conditions": "Sleep Disturbances", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07839312", "url": "https://clinicaltrials.gov/study/NCT07839312", "title": "Bonafide Sleep Supplement for Menopausal Women With Sleep Complaints", "sponsor": "Bonafide Health", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-01-03", "primary_completion": "2025-07-01", "enrollment": 111, "enrollment_type": "Actual", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-24", "first_posted": "2026-09-24", "results_posted": "", "conditions": "Sleep Disturbance", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07490431", "url": "https://clinicaltrials.gov/study/NCT07490431", "title": "An Observational Study to Learn More About How Elinzanetant is Used and How Well it Works for Women With Menopause Symptoms in United States", "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-11-30 (est.)", "primary_completion": "2029-11-30 (est.)", "enrollment": 2400, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-09-24", "first_posted": "2026-03-24", "results_posted": "", "conditions": "Vasomotor Symptoms (VMS) Associated With Menopause", "flags": [ "Updated \u226430d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07839416", "url": "https://clinicaltrials.gov/study/NCT07839416", "title": "On the Effect of a Hybrid Health Literacy Intervention on Sexual Function and Digital Health Literacy in Menopausal Women", "sponsor": "Kahramanmaras Sutcu Imam University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-01 (est.)", "primary_completion": "2026-11-05 (est.)", "enrollment": 128, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-09-24", "first_posted": "2026-09-24", "results_posted": "", "conditions": "Postmenopause; Sexual Function; Health Literacy; Digital Health Literacy", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07216742", "url": "https://clinicaltrials.gov/study/NCT07216742", "title": "Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.", "sponsor": "Granata Bio Corporation", "sponsor_class": "INDUSTRY", "phase": "Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-11-01", "primary_completion": "2028-11 (est.)", "enrollment": 659, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-24", "first_posted": "2025-10-15", "results_posted": "", "conditions": "Infertility (IVF Patients)", "flags": [ "Updated \u226430d" ], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06774885", "url": "https://clinicaltrials.gov/study/NCT06774885", "title": "Role of Folic Acid in the Management of Adjuvant Endocrine Therapy-Induced Hot Flashes in Breast Cancer Patients", "sponsor": "Future University in Egypt", "sponsor_class": "OTHER", "phase": "Phase 3", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-04-05", "primary_completion": "2025-10-22", "enrollment": 120, "enrollment_type": "Actual", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2026-09-23", "first_posted": "2025-01-14", "results_posted": "", "conditions": "THERAPY-INDUCED HOT FLASHES IN BREAST CANCER PATIENTS", "flags": [ "Updated \u226430d" ], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT07834944", "url": "https://clinicaltrials.gov/study/NCT07834944", "title": "ROSA-B: ALAN Exposure and Brain Health in Midlife Women With VMS", "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-11-01 (est.)", "primary_completion": "2030-11-01 (est.)", "enrollment": 66, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-09-22", "first_posted": "2026-09-22", "results_posted": "", "conditions": "Women in the Menopausal Period", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06440967", "url": "https://clinicaltrials.gov/study/NCT06440967", "title": "A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy", "sponsor": "Astellas Pharma Global Development, Inc.", "sponsor_class": "INDUSTRY", "phase": "Phase 3", "study_type": "Interventional", "status_code": "ACTIVE_NOT_RECRUITING", "status": "Active, not recruiting", "open": false, "start": "2024-07-31", "primary_completion": "2026-06-25", "enrollment": 982, "enrollment_type": "Actual", "countries": [ "Canada", "Czechia", "Denmark", "France", "Germany", "Hungary", "Italy", "Netherlands", "Poland", "Spain", "United Kingdom" ], "sex": "Female", "last_update": "2026-09-22", "first_posted": "2024-06-04", "results_posted": "", "conditions": "Hot Flashes", "flags": [ "Updated \u226430d" ], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT07351006", "url": "https://clinicaltrials.gov/study/NCT07351006", "title": "Exercise as Medicine: A Non-Pharmacological Approach to Menopausal Symptoms", "sponsor": "Linnaeus University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-11-01", "primary_completion": "2027-05 (est.)", "enrollment": 45, "enrollment_type": "Estimated", "countries": [ "Sweden" ], "sex": "Female", "last_update": "2026-09-22", "first_posted": "2026-01-20", "results_posted": "", "conditions": "Menopause Syndrome; Sleep Disturbance", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07834216", "url": "https://clinicaltrials.gov/study/NCT07834216", "title": "The Effect of Structured Health Information-Seeking Training on Cyberchondria and E-Health Literacy in Menopausal Women: A Randomized Controlled Trial", "sponsor": "Istanbul University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2027-01-24 (est.)", "primary_completion": "2027-03-30 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-09-22", "first_posted": "2026-09-22", "results_posted": "", "conditions": "Perimenopause; Postmenopause; Cyberchondria; E-Health Literacy", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07834463", "url": "https://clinicaltrials.gov/study/NCT07834463", "title": "Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)", "sponsor": "India Glycols Ltd", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-09-01", "primary_completion": "2027-08-31 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-22", "first_posted": "2026-09-22", "results_posted": "", "conditions": "Menopause; Hot Flashes", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06976112", "url": "https://clinicaltrials.gov/study/NCT06976112", "title": "Impact of Lean Pork on Endothelial Function in Perimenopause", "sponsor": "Pennington Biomedical Research Center", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-08-01", "primary_completion": "2026-12-31 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-22", "first_posted": "2025-05-16", "results_posted": "", "conditions": "Cardiovascular Outcome; Overweight and Obese Women; Perimenopausal Women; Vasomotor Symptoms (VMS)", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "EU CTIS", "id": "2024-510719-31-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2024-510719-31-00", "title": "A Randomized, Placebo-controlled, Double-blind, Phase 3 Clinical Study to Investigate the Efficacy and Safety of Fezolinetant for Treatment of Moderate to Severe Vasomotor Symptoms (Hot Flashes) in Women with Stage 0 to 3 Hormone Receptor-positive Breast Cancer Who Are Receiving Adjuvant Endocrine Therapy", "sponsor": "Astellas Pharma Global Development Inc.", "sponsor_class": "Pharmaceutical company", "phase": "Therapeutic confirmatory (Phase III)", "study_type": "Interventional", "status_code": 5, "status": "Ongoing, recruitment ended", "open": false, "start": "2025-01-24", "primary_completion": "", "enrollment": "383", "enrollment_type": "Planned", "countries": [ "Czechia", "Denmark", "France", "Germany", "Hungary", "Italy", "Netherlands", "Poland", "Spain" ], "sex": "Female", "last_update": "2026-09-22", "first_posted": "2024-10-01", "results_posted": "", "conditions": "Moderate to Severe Vasomotor Symptoms (VMS)", "flags": [ "Updated \u226430d" ], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT07824947", "url": "https://clinicaltrials.gov/study/NCT07824947", "title": "Effects of Strength Training on the Gait and Pelvic Floor in Menopausal Women", "sponsor": "University of Alcala", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2023-04-01", "primary_completion": "2023-07-31", "enrollment": 34, "enrollment_type": "Actual", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-09-21", "first_posted": "2026-09-17", "results_posted": "", "conditions": "Menopause; Gait, Unsteady; Pelvic Floor Disorders", "flags": [ "New", "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07653620", "url": "https://clinicaltrials.gov/study/NCT07653620", "title": "Hydration & Female Life Stages", "sponsor": "PepsiCo Global R&D", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-06-29", "primary_completion": "2026-11 (est.)", "enrollment": 72, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-21", "first_posted": "2026-06-17", "results_posted": "", "conditions": "Dehydration; Menstruation; Pre-menopause; Peri-menopausal Women; Post-menopausal Women; Hydration", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06425978", "url": "https://clinicaltrials.gov/study/NCT06425978", "title": "Efficacy of the Use of Cellular Matrix/ A-CP-HA Kit", "sponsor": "Fundaci\u00f3n Santiago Dexeus Font", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2024-05-30", "primary_completion": "2026-03-23", "enrollment": 192, "enrollment_type": "Actual", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-09-21", "first_posted": "2024-05-23", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [ "Updated \u226430d" ], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07831499", "url": "https://clinicaltrials.gov/study/NCT07831499", "title": "Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health", "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-07-15", "primary_completion": "2028-07-15 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-21", "first_posted": "2026-09-21", "results_posted": "", "conditions": "Menopause; Healthy Adult; Brain; Postmenopausal", "flags": [ "New", "Updated \u226430d" ], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07574216", "url": "https://clinicaltrials.gov/study/NCT07574216", "title": "VEDA Study (DHEA vs Estradiol)", "sponsor": "University of Arizona", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-08-04", "primary_completion": "2031-12-31 (est.)", "enrollment": 324, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-21", "first_posted": "2026-05-07", "results_posted": "", "conditions": "Post-menopause; Pre-menopause; Sexual Function; Menopause; Vaginal Dryness; Painful Intercourse", "flags": [ "Updated \u226430d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07824648", "url": "https://clinicaltrials.gov/study/NCT07824648", "title": "Thermoregulatory Physiology of Menopausal Hot Flashes", "sponsor": "SRI International", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-05-05", "primary_completion": "2027-09-15 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-17", "first_posted": "2026-09-17", "results_posted": "", "conditions": "Menopause Hot Flashes", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07800793", "url": "https://clinicaltrials.gov/study/NCT07800793", "title": "Effects of a Mobile Game in Menopausal Women", "sponsor": "Medipol University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-15 (est.)", "primary_completion": "2027-09-15 (est.)", "enrollment": 82, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-09-17", "first_posted": "2026-09-02", "results_posted": "", "conditions": "Menopause; Brain Fog; Psychological Well-being", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07260604", "url": "https://clinicaltrials.gov/study/NCT07260604", "title": "HIFEM for Incontinence After Menopause High-Intensity Focused Electromagnetic (HIFEM)", "sponsor": "G\u00f6teborg University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-15 (est.)", "primary_completion": "2027-12-31 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Sweden" ], "sex": "Female", "last_update": "2026-09-15", "first_posted": "2025-12-03", "results_posted": "", "conditions": "Urinary Incontinence (UI)", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07132385", "url": "https://clinicaltrials.gov/study/NCT07132385", "title": "Feasibility of Different Types of Exercise Training in Perimenopausal Females", "sponsor": "University of Toronto", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-09-01", "primary_completion": "2026-12-30 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2026-09-15", "first_posted": "2025-08-20", "results_posted": "", "conditions": "Women", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07751029", "url": "https://clinicaltrials.gov/study/NCT07751029", "title": "Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women", "sponsor": "Spectrum Clinical Research, LLC", "sponsor_class": "NETWORK", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-09-21 (est.)", "primary_completion": "2026-10 (est.)", "enrollment": 25, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-09-11", "first_posted": "2026-08-06", "results_posted": "", "conditions": "Menopause; 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An Observational, Cross-sectional Study", "sponsor": "Fondazione IRCCS Policlinico San Matteo di Pavia", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09 (est.)", "primary_completion": "2028-09 (est.)", "enrollment": 300, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2026-08-25", "first_posted": "2026-08-25", "results_posted": "", "conditions": "Autoimmune Diseases; Menopause", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07782853", "url": "https://clinicaltrials.gov/study/NCT07782853", "title": "A Randomized, Double-blind, Placebo-controlled, Parallel Study to Assess the Effect of Sinetrol on Body Composition &Metabolic Health in Peri-menopausal/Early Menopausal Women", "sponsor": "DR Healthcare - biotexia", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09 (est.)", "primary_completion": "2028-08 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-08-24", "first_posted": "2026-08-24", "results_posted": "", "conditions": "to Assess Changes in Body Composition After Dietary Supplementation With Sinetrol", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07548307", "url": "https://clinicaltrials.gov/study/NCT07548307", "title": "Radicle Revive\u2122: A Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Associated Health Outcomes and Related Health Outcomes", "sponsor": "Radicle Science", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "ACTIVE_NOT_RECRUITING", "status": "Active, not recruiting", "open": false, "start": "2026-04-09", "primary_completion": "2027-04-07 (est.)", "enrollment": 990, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-20", "first_posted": "2026-04-23", "results_posted": "", "conditions": "Cognitive Function", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "EU CTIS", "id": "2026-526442-28-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2026-526442-28-00", "title": "Effects of Menopausal Hormone Therapy on QTc in Genetically Confirmed Long QT Syndrome: A Prospective Randomized Sequential Crossover Study with Long-Term Observational Follow-Up (LQTS-HER)", "sponsor": "Oslo Universitetssykehus HF", "sponsor_class": "Hospital/Clinic/Other health care facility", "phase": "Therapeutic use (Phase IV)", "study_type": "Interventional", "status_code": 2, "status": "Authorised, recruitment pending", "open": true, "start": "", "primary_completion": "", "enrollment": "15", "enrollment_type": "Planned", "countries": [ "Norway" ], "sex": "Female", "last_update": "2026-08-20", "first_posted": "2026-08-20", "results_posted": "", "conditions": "Long QT syndrome", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07771946", "url": "https://clinicaltrials.gov/study/NCT07771946", "title": "Audio-Described Menopause Education Program in Visually Impaired Women", "sponsor": "Ankara University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-02-15", "primary_completion": "2025-07-15", "enrollment": 46, "enrollment_type": "Actual", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-08-19", "first_posted": "2026-08-19", "results_posted": "", "conditions": "Menopause; Visual Impairment and Blindness (Excl Colour Blindness); Menopausal Symptoms; Women's Health Education", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07606664", "url": "https://clinicaltrials.gov/study/NCT07606664", "title": "Fezolinetant and Vascular Health and Brain Health", "sponsor": "Rebecca Thurston", "sponsor_class": "OTHER", "phase": "Phase 3", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09-25 (est.)", "primary_completion": "2029-11-30 (est.)", "enrollment": 220, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-19", "first_posted": "2026-05-26", "results_posted": "", "conditions": "Menopause Hot Flashes", "flags": [ "Updated \u226490d" ], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT07594002", "url": "https://clinicaltrials.gov/study/NCT07594002", "title": "Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy", "sponsor": "University of Kentucky", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-08-13", "primary_completion": "2028-08-31 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "All", "last_update": "2026-08-18", "first_posted": "2026-05-18", "results_posted": "", "conditions": "Accupuncture; Prostate Cancer; Hormone Therapy; Hot Flashes", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07660315", "url": "https://clinicaltrials.gov/study/NCT07660315", "title": "Goji Berry and Vasomotor Symptoms Pilot Study", "sponsor": "University of California, Davis", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-25 (est.)", "primary_completion": "2027-06-30 (est.)", "enrollment": 6, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-18", "first_posted": "2026-06-22", "results_posted": "", "conditions": "Vasomotor Symptoms", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07767318", "url": "https://clinicaltrials.gov/study/NCT07767318", "title": "Therapeutic Touch and Foot Reflexology on Sleep Quality and Menopausal Symptoms", "sponsor": "Osmaniye Korkut Ata University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-08-15", "primary_completion": "2026-01-15", "enrollment": 155, "enrollment_type": "Actual", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-08-17", "first_posted": "2026-08-17", "results_posted": "", "conditions": "Complementary Alternative Medicine; Menopause; Sleep Disturbance", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT03681678", "url": "https://clinicaltrials.gov/study/NCT03681678", "title": "Laser Therapy for Treatment of Urogenital Symptoms in Women", "sponsor": "Corewell Health East", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2018-10-08", "primary_completion": "2022-12-15", "enrollment": 100, "enrollment_type": "Actual", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-17", "first_posted": "2018-09-24", "results_posted": "2024-10-16", "conditions": "Genitourinary System; Disorder, Female; Burning Vagina; Dyspareunia; Irritation; Vagina; Menopause Related Conditions; Urinary Incontinence; Urinary Bladder, Overactive; Urinary Tract Infections; Stress Urinary Incontinence", "flags": [ "Updated \u226490d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06925139", "url": "https://clinicaltrials.gov/study/NCT06925139", "title": "Efficacy of Non-Ablative Radiofrequency on Vaginal and Sexual Health in Postmenopausal Women", "sponsor": "University of Castilla-La Mancha", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2024-06-15", "primary_completion": "2024-12-30", "enrollment": 62, "enrollment_type": "Actual", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-08-17", "first_posted": "2025-04-13", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause; Vaginal Health; Sexual Dysfunction", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07533097", "url": "https://clinicaltrials.gov/study/NCT07533097", "title": "The Effect of Cold Packs on Hot Flushes and Depression in Women Going Through the Climacteric Period", "sponsor": "Rabia Atilla", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2026-04-13", "primary_completion": "2026-08-01", "enrollment": 60, "enrollment_type": "Actual", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-08-13", "first_posted": "2026-04-16", "results_posted": "", "conditions": "Hot Flashes; Climactericum; Perimenopausal Depression; Cold Application; Acupoints", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06826755", "url": "https://clinicaltrials.gov/study/NCT06826755", "title": "Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial", "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-05-23", "primary_completion": "2027-09 (est.)", "enrollment": 70, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-13", "first_posted": "2025-02-14", "results_posted": "", "conditions": "Perimenopause; Hypertension", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07763509", "url": "https://clinicaltrials.gov/study/NCT07763509", "title": "Calcium-Rich Food Versus Calcium Carbonate for Bone Health", "sponsor": "Cornell University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09-01 (est.)", "primary_completion": "2027-06-01 (est.)", "enrollment": 217, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-13", "first_posted": "2026-08-13", "results_posted": "", "conditions": "Osteopenia; Osteoporosis; Bone Health in Perimenopausal Women; Menopause Related Conditions; Fracture Healing", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07762287", "url": "https://clinicaltrials.gov/study/NCT07762287", "title": "Evaluation of Possible Ways the Body May Process Two Different Forms of Elinzanetant in Healthy Study Participants", "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "phase": "Phase 1", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-07-22", "primary_completion": "2027-02-22 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2026-08-13", "first_posted": "2026-08-13", "results_posted": "", "conditions": "Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT07759830", "url": "https://clinicaltrials.gov/study/NCT07759830", "title": "A Feasibility Study of a Group Talking Therapy Programme for NHS Staff With Menopausal Hot Flushes and Night Sweats.", "sponsor": "Queen's University, Belfast", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-05-08", "primary_completion": "2026-01-30", "enrollment": 35, "enrollment_type": "Actual", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-08-12", "first_posted": "2026-08-12", "results_posted": "", "conditions": "Vasomotor Symptoms Associated With Menopause", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07759908", "url": "https://clinicaltrials.gov/study/NCT07759908", "title": "Effects of a Synbiotic Intervention on Perimenopausal/Menopausal Symptoms", "sponsor": "University College Cork", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-06-06", "primary_completion": "2025-09-30", "enrollment": 49, "enrollment_type": "Actual", "countries": [ "Ireland" ], "sex": "Female", "last_update": "2026-08-12", "first_posted": "2026-08-12", "results_posted": "", "conditions": "Menopause; Perimenopause; Perimenopausal Women", "flags": [ "New", "Updated \u226490d", "Ireland" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07572578", "url": "https://clinicaltrials.gov/study/NCT07572578", "title": "Radicle Women's HealthTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes Among Women Experiencing Menopausal Symptoms", "sponsor": "Radicle Science", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2026-05-07", "primary_completion": "2026-08-05", "enrollment": 502, "enrollment_type": "Actual", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-12", "first_posted": "2026-05-07", "results_posted": "", "conditions": "Fatigue", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07724522", "url": "https://clinicaltrials.gov/study/NCT07724522", "title": "Prebiotic Inulin for Late-Reproductive Individuals", "sponsor": "George Washington University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-08-01", "primary_completion": "2028-02 (est.)", "enrollment": 27, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-11", "first_posted": "2026-07-24", "results_posted": "", "conditions": "Obesity & Overweight; Perimenopausal Women; Prebiotics; Inulin; Muscle, Skeletal; Cardiovascular Diseases (CVD); Microbiota; Gastrointestinal Microbiome; Dietary Fiber; Women Health; Vascular Health; Insulin Resistance", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07752641", "url": "https://clinicaltrials.gov/study/NCT07752641", "title": "Effect of HIFAS MENOPAUSE on Quality of Life in Postmenopausal Women", "sponsor": "Hifas da Terra S.L.", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-02-14", "primary_completion": "2026-01-14", "enrollment": 20, "enrollment_type": "Actual", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-08-11", "first_posted": "2026-08-07", "results_posted": "", "conditions": "Menopause; Menopausal Symptoms", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07455812", "url": "https://clinicaltrials.gov/study/NCT07455812", "title": "A Study in Germany to Learn About the Value of Fezolinetant in Treating Hot Flashes and Night Sweats in Women During Menopause", "sponsor": "Astellas Pharma Europe Ltd.", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2024-10-29", "primary_completion": "2026-07-16", "enrollment": 105, "enrollment_type": "Actual", "countries": [ "Germany" ], "sex": "Female", "last_update": "2026-08-10", "first_posted": "2026-03-06", "results_posted": "", "conditions": "Hot Flashes", "flags": [ "Updated \u226490d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07754630", "url": "https://clinicaltrials.gov/study/NCT07754630", "title": "Analysis of the Hormonal Implant and Transdermal Estradiol Gel in Climacteric Women", "sponsor": "Nutrindo Ideais Research Center", "sponsor_class": "NETWORK", "phase": "Phase 2", "study_type": "Interventional", "status_code": "ACTIVE_NOT_RECRUITING", "status": "Active, not recruiting", "open": false, "start": "2025-02-25", "primary_completion": "2026-05-01", "enrollment": 50, "enrollment_type": "Actual", "countries": [ "Brazil" ], "sex": "Female", "last_update": "2026-08-10", "first_posted": "2026-08-10", "results_posted": "", "conditions": "Menopause; Hypoestrogenism; Hormonal Therapy", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT07750080", "url": "https://clinicaltrials.gov/study/NCT07750080", "title": "The Effect of Multimodal Approach of Electrotherapy Versus Shock Wave Therapy in Menopausal Women With Tennis Elbow.", "sponsor": "October 6 University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-03", "primary_completion": "2026-08-03 (est.)", "enrollment": 45, "enrollment_type": "Estimated", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2026-08-06", "first_posted": "2026-08-06", "results_posted": "", "conditions": "Shock Wave", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07242430", "url": "https://clinicaltrials.gov/study/NCT07242430", "title": "12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being.", "sponsor": "Northumbria University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "ACTIVE_NOT_RECRUITING", "status": "Active, not recruiting", "open": false, "start": "2026-04-07", "primary_completion": "2026-10-25 (est.)", "enrollment": 58, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-08-05", "first_posted": "2025-11-21", "results_posted": "", "conditions": "Perimenopause; Perimenopausal Women; Perimenopause, Climacteric Syndrome", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06678880", "url": "https://clinicaltrials.gov/study/NCT06678880", "title": "Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction", "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-03-11", "primary_completion": "2028-12 (est.)", "enrollment": 120, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-05", "first_posted": "2024-11-07", "results_posted": "", "conditions": "Depression; Depression During the Menopausal Transition; Menopausal Depression", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07235878", "url": "https://clinicaltrials.gov/study/NCT07235878", "title": "12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being", "sponsor": "Northumbria University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "ACTIVE_NOT_RECRUITING", "status": "Active, not recruiting", "open": false, "start": "2025-12-09", "primary_completion": "2026-10-18 (est.)", "enrollment": 58, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-08-05", "first_posted": "2025-11-19", "results_posted": "", "conditions": "Perimenopause; Perimenopausal Women; Perimenopause, Climacteric Syndrome", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06978504", "url": "https://clinicaltrials.gov/study/NCT06978504", "title": "Impact of Genetic Polymorphisms And DASH Diet On Weight Loss Progression In Climacteric Women With Metabolic Syndrome", "sponsor": "Nutrindo Ideais Research Center", "sponsor_class": "NETWORK", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2025-04-01", "primary_completion": "2025-08-01", "enrollment": 30, "enrollment_type": "Actual", "countries": [ "Brazil" ], "sex": "Female", "last_update": "2026-08-04", "first_posted": "2025-05-18", "results_posted": "", "conditions": "Nutrition; Metabolic Syndrome; Obesity; Weight Loss; Genetic Polymorphisms", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07022340", "url": "https://clinicaltrials.gov/study/NCT07022340", "title": "Hemodynamics After Resistance Training", "sponsor": "University of Michigan", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-06-06", "primary_completion": "2026-12 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-08-03", "first_posted": "2025-06-15", "results_posted": "", "conditions": "Perimenopause", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07742488", "url": "https://clinicaltrials.gov/study/NCT07742488", "title": "Effects of Statins and Hormone Replacement Therapy in Coagulation Profile of Menopausal Women With Dyslipidemia", "sponsor": "University of Pisa", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-10-15", "primary_completion": "2029-12 (est.)", "enrollment": 70, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2026-08-03", "first_posted": "2026-08-03", "results_posted": "", "conditions": "Menopausal Complaints; Hypercholerolemia; Coagulation Tests", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07394049", "url": "https://clinicaltrials.gov/study/NCT07394049", "title": "A Prospective Multicenter Cohort Study of Contemporary Menopausal Hormone Therapy and Cardiovascular Outcomes", "sponsor": "Heinrich-Heine University, Duesseldorf", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-08-01 (est.)", "primary_completion": "2041-03 (est.)", "enrollment": 3408, "enrollment_type": "Estimated", "countries": [ "Germany" ], "sex": "Female", "last_update": "2026-07-31", "first_posted": "2026-02-06", "results_posted": "", "conditions": "Hormone Replacement Therapy; Cardiovascular Diseases; Hormone Replacement Therapy, Post-Menopausal; Menopause", "flags": [ "Updated \u226490d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07738211", "url": "https://clinicaltrials.gov/study/NCT07738211", "title": "Laughter Yoga, Emotional Labor, and Menopause-Specific Quality of Life in Nurses", "sponsor": "Inonu University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "ACTIVE_NOT_RECRUITING", "status": "Active, not recruiting", "open": false, "start": "2025-07-25", "primary_completion": "2026-07-25", "enrollment": 120, "enrollment_type": "Actual", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-07-31", "first_posted": "2026-07-31", "results_posted": "", "conditions": "Menopause; Menopause-Related Quality of Life; Emotional Labor; Nurse", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07739615", "url": "https://clinicaltrials.gov/study/NCT07739615", "title": "Effect of Soya Bean on the Female Reproductive Hormones and Menopausal Symptoms", "sponsor": "Alex Ekwueme Federal University Teaching Hospital", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-08-01 (est.)", "primary_completion": "2026-08-30 (est.)", "enrollment": 69, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-31", "first_posted": "2026-07-31", "results_posted": "", "conditions": "Menopausal Syndrome", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07737613", "url": "https://clinicaltrials.gov/study/NCT07737613", "title": "Acute Effects of Estradiol Administration on Brain Function During Fear Learning", "sponsor": "University of Arizona", "sponsor_class": "OTHER", "phase": "Early Phase 1", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-08 (est.)", "primary_completion": "2027-08 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-30", "first_posted": "2026-07-30", "results_posted": "", "conditions": "PTSD and Trauma-related Symptoms; Cognitive Decline in Older Adults; Post Menopausal Women", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Early Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT07737691", "url": "https://clinicaltrials.gov/study/NCT07737691", "title": "Relaxation Training Via Tele-Rehabilitation in Postmenopausal Women", "sponsor": "Marmara University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-08-01 (est.)", "primary_completion": "2026-09-20 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-30", "first_posted": "2026-07-30", "results_posted": "", "conditions": "Postmenopausal Symptoms; Telerehabilitation; Relaxation Training; Menopause; Menopausal Syndrome", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07737782", "url": "https://clinicaltrials.gov/study/NCT07737782", "title": "Retrospective Cohort Study of Symptoms and Quality of Life in Women With Genitourinary Syndrome of Menopause.", "sponsor": "Mucosa Innovations, S.L.", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07 (est.)", "primary_completion": "2026-09 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-07-30", "first_posted": "2026-07-30", "results_posted": "", "conditions": "Vulvar Atrophy; Vulvovaginal Signs and Symptoms; Genitourinary Syndrome of Menopause (GSM); Quality of Life; Menopause Related Conditions; Dyspareunia; Urinary Incontinence, Urgency-frequency; Sexual Function; Women\u00b4s Health; Vaginal Dryness", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07705724", "url": "https://clinicaltrials.gov/study/NCT07705724", "title": "Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women", "sponsor": "University of Arkansas", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-01 (est.)", "primary_completion": "2028-10-01 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-30", "first_posted": "2026-07-15", "results_posted": "", "conditions": "Obesity & Overweight; Women; Menopause", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07732452", "url": "https://clinicaltrials.gov/study/NCT07732452", "title": "Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition", "sponsor": "McGill University Health Centre/Research Institute of the McGill University Health Centre", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-11 (est.)", "primary_completion": "2028-11 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-29", "first_posted": "2026-07-29", "results_posted": "", "conditions": "Menopause; Perimenopause; Vasomotor Symptoms; Cardiovascular Disease Risk Factor; Menopausal Hormone Therapy; Cardiac Remodeling; Myocardial Fibrosis; Microvascular Dysfunction; Cognitive Function Assessment", "flags": [ "New", "Updated \u226490d" ], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07729930", "url": "https://clinicaltrials.gov/study/NCT07729930", "title": "Dietary Supplements and Middle Aged Women (Creatine)", "sponsor": "Loughborough University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-05-01", "primary_completion": "2028-11-01 (est.)", "enrollment": 38, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-07-28", "first_posted": "2026-07-28", "results_posted": "", "conditions": "Cognition; Muscle Strength; Fatigue Symptom; Blood Pressure and Augmentation Index; Body Composition Changes; Sleep; Gastrointestinal Comfort; Quality of Life; Joint Pain; Inflammation Biomarkers; Bone Metabolism Biomarkers; Menopause Symptoms", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07596069", "url": "https://clinicaltrials.gov/study/NCT07596069", "title": "Prevalence of Menopause-associated Symptoms Throughout the Menopausal Transition in Women Aged 40 to 70 Residing in Spain and Its Relationship With Physical Activity - MdH Study", "sponsor": "Cuerpos Serranos S.L.", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-18", "primary_completion": "2026-09 (est.)", "enrollment": 15000, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-07-28", "first_posted": "2026-05-19", "results_posted": "", "conditions": "Menopausal Symptoms; Physical Activity and Sedentary Behavior", "flags": [ "Updated \u226490d" ], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07628790", "url": "https://clinicaltrials.gov/study/NCT07628790", "title": "Feasibility of Lower-Body EMS Resistance Training in Postmenopausal Women", "sponsor": "Seoul National University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "COMPLETED", "status": "Completed", "open": false, "start": "2026-06-01", "primary_completion": "2026-07-27", "enrollment": 16, "enrollment_type": "Actual", "countries": [ "South Korea" ], "sex": "Female", "last_update": "2026-07-28", "first_posted": "2026-06-05", "results_posted": "", "conditions": "Post Menopausal; Resistance Exercise; Body Composition; Autonomic Function", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07526948", "url": "https://clinicaltrials.gov/study/NCT07526948", "title": "Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV", "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09 (est.)", "primary_completion": "2029-09-30 (est.)", "enrollment": 62, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-28", "first_posted": "2026-04-14", "results_posted": "", "conditions": "Menopausal Complaints; Vaginal Atrophy; Genitourinary Symptoms; HIV (Human Immunodeficiency Virus); Menopause Related Conditions; Vaginitis; Perimenopause", "flags": [ "Updated \u226490d" ], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07728461", "url": "https://clinicaltrials.gov/study/NCT07728461", "title": "Menopause and Compassionate Living Education", "sponsor": "Ataturk University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09-30 (est.)", "primary_completion": "2026-12-15 (est.)", "enrollment": 68, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-07-27", "first_posted": "2026-07-27", "results_posted": "", "conditions": "Mindfulness Compassionate Living Training", "flags": [ "New", "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07365514", "url": "https://clinicaltrials.gov/study/NCT07365514", "title": "Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females", "sponsor": "University of Connecticut", "sponsor_class": "OTHER", "phase": "Phase 1", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-07 (est.)", "primary_completion": "2028-02 (est.)", "enrollment": 159, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-23", "first_posted": "2026-01-26", "results_posted": "", "conditions": "Postmenopausal Osteoporosis; Gut Microbiome; Menopause", "flags": [ "Updated \u226490d" ], "phase_group": "Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT06673004", "url": "https://clinicaltrials.gov/study/NCT06673004", "title": "Ovarian Tissue Allo-transplantation", "sponsor": "University Hospitals Cleveland Medical Center", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09-01 (est.)", "primary_completion": "2030-05-30 (est.)", "enrollment": 10, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-23", "first_posted": "2024-11-04", "results_posted": "", "conditions": "Ovarian Failure; Ovarian Insufficiency; Menopause Ovarian Failure; Menopause, Premature; Infertility, Female; Endocrine Female Infertility", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07713862", "url": "https://clinicaltrials.gov/study/NCT07713862", "title": "Midlife Empowerment and Longevity Through Optimizing Wellness", "sponsor": "National University Health System, Singapore", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2027-01 (est.)", "primary_completion": "2029-01 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-23", "first_posted": "2026-07-20", "results_posted": "", "conditions": "Menopause", "flags": [ "Updated \u226490d" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07401810", "url": "https://clinicaltrials.gov/study/NCT07401810", "title": "Fascial Yoga in Menopausal Women", "sponsor": "Marmara University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07-01 (est.)", "primary_completion": "2026-09-01 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-22", "first_posted": "2026-02-10", "results_posted": "", "conditions": "Menopause; Stress, Psychological; Cognitive Flexibility; Nonpharmacological Interventions; Randomized Controlled Trial; Cognitive Control; Perceived Stress; Yoga", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06975111", "url": "https://clinicaltrials.gov/study/NCT06975111", "title": "Focusing on the Menopausal Transition to Improve Mid-Life Women's Health", "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "phase": "Phase 2, Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-01", "primary_completion": "2029-10-31 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-21", "first_posted": "2025-05-16", "results_posted": "", "conditions": "Menopause; Menopause Hot Flashes; Menopause Related Conditions; Cardiovascular", "flags": [], "phase_group": "Phase 2/3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06480695", "url": "https://clinicaltrials.gov/study/NCT06480695", "title": "Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females", "sponsor": "University of Virginia", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-01", "primary_completion": "2026-12-31 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-17", "first_posted": "2024-06-28", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07615777", "url": "https://clinicaltrials.gov/study/NCT07615777", "title": "Nutritional Supplementation on Physiological and Metabolic Markers in Females", "sponsor": "University of Southampton", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-07-09", "primary_completion": "2026-12 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-07-13", "first_posted": "2026-05-29", "results_posted": "", "conditions": "Perimenopausal Women; Body Composition Changes", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07697768", "url": "https://clinicaltrials.gov/study/NCT07697768", "title": "Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment", "sponsor": "Patricia Lordelo", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07-30 (est.)", "primary_completion": "2027-06-30 (est.)", "enrollment": 150, "enrollment_type": "Estimated", "countries": [ "Brazil" ], "sex": "Female", "last_update": "2026-07-13", "first_posted": "2026-07-13", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause (GSM); Bacterial Vaginosis; Vulvovaginal Candidiasis (VVC)", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07695376", "url": "https://clinicaltrials.gov/study/NCT07695376", "title": "CARAMEL Observational Study", "sponsor": "Biogipuzkoa Health Research Institute", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-16", "primary_completion": "2028-05 (est.)", "enrollment": 3000, "enrollment_type": "Estimated", "countries": [ "Colombia", "Croatia", "Greece", "Lithuania", "Spain" ], "sex": "Female", "last_update": "2026-07-10", "first_posted": "2026-07-10", "results_posted": "", "conditions": "Perimenopause; Menopause; Cardiovascular (CV) Risk; Women (Between 30 to 60 Years Old); Cardiovascular Disease Risk Factor; Artificial Intelligence (Al)", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07690137", "url": "https://clinicaltrials.gov/study/NCT07690137", "title": "Pelvic Floor Symptoms Across Menopausel Stages", "sponsor": "Bezmialem Vakif University", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07-06 (est.)", "primary_completion": "2026-09-06 (est.)", "enrollment": 180, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-07-09", "first_posted": "2026-07-08", "results_posted": "", "conditions": "Menopause; Perimenopausal Disorder", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06743269", "url": "https://clinicaltrials.gov/study/NCT06743269", "title": "Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women", "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-03-27", "primary_completion": "2027-01-01 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-09", "first_posted": "2024-12-19", "results_posted": "", "conditions": "Menopause; Hot Flashes; Blood Pressure Regulation", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT03916978", "url": "https://clinicaltrials.gov/study/NCT03916978", "title": "Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women", "sponsor": "Genesis Athens Clinic", "sponsor_class": "OTHER", "phase": "Phase 2, Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2019-05-21", "primary_completion": "2027-01-30 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Greece" ], "sex": "Female", "last_update": "2026-07-08", "first_posted": "2019-04-16", "results_posted": "", "conditions": "Infertility, Female; Anovulatory Infertility; Menopause; Amenorrhea", "flags": [], "phase_group": "Phase 2/3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06889753", "url": "https://clinicaltrials.gov/study/NCT06889753", "title": "A Clinical Trial to Investigate the Effect of Pollen Extracts on Menopausal Symptoms in Healthy Women.", "sponsor": "Graminex LLC", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-10-29", "primary_completion": "2026-08 (est.)", "enrollment": 120, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2026-07-08", "first_posted": "2025-03-21", "results_posted": "", "conditions": "Menopausal Women", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT04031456", "url": "https://clinicaltrials.gov/study/NCT04031456", "title": "Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients", "sponsor": "Genesis Athens Clinic", "sponsor_class": "OTHER", "phase": "Phase 2, Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2019-07-30", "primary_completion": "2027-01-30 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Greece" ], "sex": "Female", "last_update": "2026-07-08", "first_posted": "2019-07-24", "results_posted": "", "conditions": "Menopause, Premature; Menopause Related Conditions; Menopausal Syndrome; Premature Ovarian Failure; Ovarian Failure, Premature", "flags": [], "phase_group": "Phase 2/3" }, { "registry": "ClinicalTrials.gov", "id": "NCT07676604", "url": "https://clinicaltrials.gov/study/NCT07676604", "title": "Colipral\u00ae (Probiotic Strain Escherichia Coli 5C (ECP24\u00ae)) for Prevention of Recurrent Cystitis in Menopausal Women", "sponsor": "Liaquat University of Medical & Health Sciences", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07-06 (est.)", "primary_completion": "2027-07-31 (est.)", "enrollment": 134, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-06", "first_posted": "2026-06-30", "results_posted": "", "conditions": "Recurrent Cystitis", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07679074", "url": "https://clinicaltrials.gov/study/NCT07679074", "title": "CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life", "sponsor": "Samphire Group, Inc.", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-06-01", "primary_completion": "2027-01-01 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-01", "first_posted": "2026-07-01", "results_posted": "", "conditions": "Premenstrual Syndrome; Premenstrual Dysphoric Disorder; Dysmenorrhea; Endometriosis; Perimenopause; Menopause; Pelvic Pain", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07678359", "url": "https://clinicaltrials.gov/study/NCT07678359", "title": "Effect of ZenRest\u2122 Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women", "sponsor": "Nutraland USA, Inc.", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07 (est.)", "primary_completion": "2026-09 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-07-01", "first_posted": "2026-07-01", "results_posted": "", "conditions": "Sleep Quality; Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07486986", "url": "https://clinicaltrials.gov/study/NCT07486986", "title": "Endocrine Disruption, Menopause, and Poor Sleep in wOmen With Type 2 Diabetes: Effects on Cardiovascular Health", "sponsor": "Ottawa Heart Institute Research Corporation", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09 (est.)", "primary_completion": "2032-12 (est.)", "enrollment": 381, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-07-01", "first_posted": "2026-03-23", "results_posted": "", "conditions": "Menopause; Sleep Disruption; T2DM", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07427459", "url": "https://clinicaltrials.gov/study/NCT07427459", "title": "Amygdala Insula Retraining in the Management of Perimenopause Symptoms", "sponsor": "Chronic Conditions Research Fund", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-07-15 (est.)", "primary_completion": "2027-01-31 (est.)", "enrollment": 160, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-06-29", "first_posted": "2026-02-23", "results_posted": "", "conditions": "Perimenopause; Menopausal Complaints", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07672548", "url": "https://clinicaltrials.gov/study/NCT07672548", "title": "The Effects of 10-weeks Pilates Exercise on Pulmonary Function and Quality of Life in Postmenopausal Women", "sponsor": "Middle East University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-06-01", "primary_completion": "2026-07-01 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "Jordan" ], "sex": "Female", "last_update": "2026-06-29", "first_posted": "2026-06-29", "results_posted": "", "conditions": "Post Menopausal", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07657429", "url": "https://clinicaltrials.gov/study/NCT07657429", "title": "Effect of Mandala Coloring on Menopausal Attitude, Perceived Stress and Mindfulness", "sponsor": "Ondokuz May\u0131s University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-05-30 (est.)", "primary_completion": "2026-09-30 (est.)", "enrollment": 140, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-06-29", "first_posted": "2026-06-18", "results_posted": "", "conditions": "Menopause; Psychological Stress; Mindfulness", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07158021", "url": "https://clinicaltrials.gov/study/NCT07158021", "title": "Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial", "sponsor": "University of Michigan Rogel Cancer Center", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-01-22", "primary_completion": "2028-01-01 (est.)", "enrollment": 75, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-06-23", "first_posted": "2025-09-05", "results_posted": "", "conditions": "Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Breast Carcinoma", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT07314827", "url": "https://clinicaltrials.gov/study/NCT07314827", "title": "Women's Healthy Aging and Menopause; (WHAM)", "sponsor": "University of Miami", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-01 (est.)", "primary_completion": "2028-01-31 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-06-23", "first_posted": "2026-01-02", "results_posted": "", "conditions": "Meditation; Health Education", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07657078", "url": "https://clinicaltrials.gov/study/NCT07657078", "title": "Meleis' Transition Theory-Based Education and Counseling Program in Menopausal Women", "sponsor": "Ankara Medipol University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-06-15 (est.)", "primary_completion": "2026-10-15 (est.)", "enrollment": 114, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-06-22", "first_posted": "2026-06-18", "results_posted": "", "conditions": "Menopause; Menopausal Symptoms; Perimenopausal Depression", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07649356", "url": "https://clinicaltrials.gov/study/NCT07649356", "title": "Significance of Estrogen Status for Muscle Function, Physical Fitness, and Physiological Health Parameters - a Comparison of Age-matched Groups of Women Before and After Menopause.", "sponsor": "Mette Hansen", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-02-01", "primary_completion": "2027-08-01 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "Denmark" ], "sex": "Female", "last_update": "2026-06-16", "first_posted": "2026-06-16", "results_posted": "", "conditions": "Muscle Mass and Strength; Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07648667", "url": "https://clinicaltrials.gov/study/NCT07648667", "title": "Cognitive Task Sensitivity in Perimenopause and Nutritional Status", "sponsor": "Northumbria University", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-06 (est.)", "primary_completion": "2026-07 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-06-15", "first_posted": "2026-06-15", "results_posted": "", "conditions": "Perimenopause; Cognitive Function in Perimenopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07648680", "url": "https://clinicaltrials.gov/study/NCT07648680", "title": "\"Menopause Experiences in Cultural and Intercultural Contexts\"", "sponsor": "Institut Investigacio Sanitaria Pere Virgili", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-27", "primary_completion": "2028-04-22 (est.)", "enrollment": 25, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-06-15", "first_posted": "2026-06-15", "results_posted": "", "conditions": "Valid MeSH Conditions", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT05193968", "url": "https://clinicaltrials.gov/study/NCT05193968", "title": "Hot Flashes and Neurovascular Function in Women", "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2022-02-24", "primary_completion": "2026-12 (est.)", "enrollment": 120, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-06-12", "first_posted": "2022-01-18", "results_posted": "", "conditions": "Hot Flashes; Menopause; Vasomotor System; Labile", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07635017", "url": "https://clinicaltrials.gov/study/NCT07635017", "title": "Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation", "sponsor": "Carnegie Mellon University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07-01 (est.)", "primary_completion": "2028-05-01 (est.)", "enrollment": 25, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "All", "last_update": "2026-06-09", "first_posted": "2026-06-09", "results_posted": "", "conditions": "Cortical Excitability; Healthy; TMS; Menstrual Cycle; Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07136415", "url": "https://clinicaltrials.gov/study/NCT07136415", "title": "Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms", "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-02-13", "primary_completion": "2031-02 (est.)", "enrollment": 1000, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-06-08", "first_posted": "2025-08-22", "results_posted": "", "conditions": "Menopausal Women; Insomnia", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT06527248", "url": "https://clinicaltrials.gov/study/NCT06527248", "title": "Nitrate, Exercise and Vascular Function in Midlife Women", "sponsor": "University of Vienna", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-03-31", "primary_completion": "2027-03 (est.)", "enrollment": 54, "enrollment_type": "Estimated", "countries": [ "Austria" ], "sex": "Female", "last_update": "2026-06-05", "first_posted": "2024-07-30", "results_posted": "", "conditions": "Healthy; Menopause; Hypertension; Inflammation", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06917313", "url": "https://clinicaltrials.gov/study/NCT06917313", "title": "FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy", "sponsor": "Yale University", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-12-05", "primary_completion": "2028-03 (est.)", "enrollment": 92, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-06-02", "first_posted": "2025-04-08", "results_posted": "", "conditions": "Breast Cancer Early Stage Breast Cancer (Stage 1-3)", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT07618039", "url": "https://clinicaltrials.gov/study/NCT07618039", "title": "MOving Forward With MENopause Treatment Through Pharmacists' Expanded Roles in Hormone Health", "sponsor": "Dalhousie University", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-07-01 (est.)", "primary_completion": "2027-07-01 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-06-01", "first_posted": "2026-06-01", "results_posted": "", "conditions": "Menopause; Pharmacists", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07075133", "url": "https://clinicaltrials.gov/study/NCT07075133", "title": "Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes", "sponsor": "University Hospital, Toulouse", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09-15 (est.)", "primary_completion": "2029-07-15 (est.)", "enrollment": 45, "enrollment_type": "Estimated", "countries": [ "France" ], "sex": "All", "last_update": "2026-06-01", "first_posted": "2025-07-20", "results_posted": "", "conditions": "Obesity; Sarcopenia; Post Menopause; Type 2 Diabetes; Circadian Clock", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07617454", "url": "https://clinicaltrials.gov/study/NCT07617454", "title": "Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women", "sponsor": "Mette Hansen", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-02-01", "primary_completion": "2027-08-01 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "Denmark" ], "sex": "Female", "last_update": "2026-06-01", "first_posted": "2026-06-01", "results_posted": "", "conditions": "Menopause Related Conditions; Exercise Training", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07616401", "url": "https://clinicaltrials.gov/study/NCT07616401", "title": "MicroRNA and Markers and Therapeutic Response to Romosozumab and Abaloparatide in Postmenopausal Osteoporosis", "sponsor": "Istituto Auxologico Italiano", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-08-31", "primary_completion": "2029-08-31 (est.)", "enrollment": 42, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2026-06-01", "first_posted": "2026-06-01", "results_posted": "", "conditions": "Osteoporosis; Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07615790", "url": "https://clinicaltrials.gov/study/NCT07615790", "title": "Structured Combined Exercise Program in Postmenopausal Women: Effects on Heart Rate Variability and Menopausal Symptoms", "sponsor": "Fenerbahce University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-27", "primary_completion": "2026-07 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-05-29", "first_posted": "2026-05-29", "results_posted": "", "conditions": "Postmenopausal; Menopausal Symptoms; Autonomic Nervous System Diseases; Sleep Wake Disorders", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07614542", "url": "https://clinicaltrials.gov/study/NCT07614542", "title": "AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing", "sponsor": "Gulbenkian Institute for Molecular Medicine", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-06-02", "primary_completion": "2026-12 (est.)", "enrollment": 300, "enrollment_type": "Estimated", "countries": [ "Portugal" ], "sex": "Female", "last_update": "2026-05-29", "first_posted": "2026-05-29", "results_posted": "", "conditions": "Menopause; Gut Microbiome; Hormonal Changes; Chronic Low-Grade Inflammation; Inflammaging", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07606326", "url": "https://clinicaltrials.gov/study/NCT07606326", "title": "A Retrospective and Prospective Clinical Registry for Data Collection of Perimenopausal, Menopausal and Premature Ovarian Insufficiency Women", "sponsor": "IRCCS San Raffaele", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-06 (est.)", "primary_completion": "2040-12 (est.)", "enrollment": 5000, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-05-26", "first_posted": "2026-05-26", "results_posted": "", "conditions": "Menopause; Menopausal Hormone Therapy; Menopause Surgical; Menopause Related Conditions; Menopausal Complaints; Menopausal Osteoporosis; Menopause-related Hot Flashes; Menopausal and Perimenopausal Disorder, Unspecified; Menopausal and Postmenopausal Women; Premature Ovarian Failure (POF)", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07602530", "url": "https://clinicaltrials.gov/study/NCT07602530", "title": "A Study in Canada to Follow Outcomes of Women in Menopause Treated With Fezolinetant for Hot Flashes, When Given in Clinical Practice", "sponsor": "Astellas Pharma Europe Ltd.", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-10-23", "primary_completion": "2027-02-28 (est.)", "enrollment": 238, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2026-05-22", "first_posted": "2026-05-22", "results_posted": "", "conditions": "Hot Flashes", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06856174", "url": "https://clinicaltrials.gov/study/NCT06856174", "title": "Menopausal HT for Women Living With HIV (HoT)", "sponsor": "Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections", "sponsor_class": "NETWORK", "phase": "Phase 4", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-09", "primary_completion": "2027-09-20 (est.)", "enrollment": 105, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-05-22", "first_posted": "2025-03-04", "results_posted": "", "conditions": "HIV Infection; Menopause", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07603089", "url": "https://clinicaltrials.gov/study/NCT07603089", "title": "Exploring the Link Between Menopause, Glucose Control, and Frozen Shoulder in Women", "sponsor": "University of Nottingham", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-08 (est.)", "primary_completion": "2027-09 (est.)", "enrollment": 340, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-05-22", "first_posted": "2026-05-22", "results_posted": "", "conditions": "Frozen Shoulder", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07597915", "url": "https://clinicaltrials.gov/study/NCT07597915", "title": "Our Transitions: Improving the Path to Menopause With Personal Digital Health Technologies", "sponsor": "4YouandMe", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-05-01 (est.)", "primary_completion": "2027-08-31 (est.)", "enrollment": 1250, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-05-20", "first_posted": "2026-05-20", "results_posted": "", "conditions": "Perimenopause; Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07077395", "url": "https://clinicaltrials.gov/study/NCT07077395", "title": "Finding Links Between Hot flASHes and CardioVascular Disease", "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-01", "primary_completion": "2029-06 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-05-20", "first_posted": "2025-07-22", "results_posted": "", "conditions": "Menopause-related Hot Flashes", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT06490146", "url": "https://clinicaltrials.gov/study/NCT06490146", "title": "Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function", "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-04-01", "primary_completion": "2030-08-21 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-05-20", "first_posted": "2024-07-08", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07477483", "url": "https://clinicaltrials.gov/study/NCT07477483", "title": "Effect of Manuel Therapy on Tension Type Headache in Menopausal and Premenopasual Women", "sponsor": "Necmettin Erbakan University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-10-01", "primary_completion": "2026-05 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-05-20", "first_posted": "2026-03-17", "results_posted": "", "conditions": "Tension Type Headache", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07600567", "url": "https://clinicaltrials.gov/study/NCT07600567", "title": "Algal Lutein Against Decline of Intellectual Nimbleness", "sponsor": "Poznan University of Life Sciences", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-05-01 (est.)", "primary_completion": "2027-04-30 (est.)", "enrollment": 300, "enrollment_type": "Estimated", "countries": [ "Poland" ], "sex": "Female", "last_update": "2026-05-20", "first_posted": "2026-05-20", "results_posted": "", "conditions": "Menopausal Syndrome; Cognitive Decline; Obesity & Overweight; Menopause; Inflamation; Gut Dysbiosis; Bisphenol A; Cardio Vascular Disease", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07599319", "url": "https://clinicaltrials.gov/study/NCT07599319", "title": "Avatar-Based Education and Counseling for Spousal Support During Menopause", "sponsor": "Eskisehir Osmangazi University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-15", "primary_completion": "2026-12-15 (est.)", "enrollment": 280, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "All", "last_update": "2026-05-20", "first_posted": "2026-05-20", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07599930", "url": "https://clinicaltrials.gov/study/NCT07599930", "title": "Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being", "sponsor": "King's College London", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-24", "primary_completion": "2026-12 (est.)", "enrollment": 20, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-05-20", "first_posted": "2026-05-20", "results_posted": "", "conditions": "Perimenopause; Perimenopause-Related Depression; Mood; Sleep; Quality of Life; Gut -Microbiota", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07596368", "url": "https://clinicaltrials.gov/study/NCT07596368", "title": "THE EFFECT OF MOTIVATIONAL INTERVIEWING ON MENOPAUSE MYTHS AND POSTTRAUMATIC GROWTH IN POSTMENOPAUSAL WOMEN:RANDOMIZED CONTROLLED STUDY", "sponsor": "Inonu University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-05 (est.)", "primary_completion": "2026-10 (est.)", "enrollment": 96, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-05-19", "first_posted": "2026-05-19", "results_posted": "", "conditions": "Menopause; Postmenopausal State", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06419972", "url": "https://clinicaltrials.gov/study/NCT06419972", "title": "Multimodal Program for Climacteric Women", "sponsor": "University of Valencia", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-05-30", "primary_completion": "2026-10-25 (est.)", "enrollment": 115, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-05-19", "first_posted": "2024-05-17", "results_posted": "", "conditions": "Climacteric Syndrome; Postmenopausal Symptoms; Menopause; Perimenopausal Disorder", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07590999", "url": "https://clinicaltrials.gov/study/NCT07590999", "title": "Probiotic Intake and Perimenopausal Psychological Assessments", "sponsor": "University of Oxford", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-11-12", "primary_completion": "2027-06-30 (est.)", "enrollment": 106, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-05-15", "first_posted": "2026-05-15", "results_posted": "", "conditions": "Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations; Perimenopause; Perimenopause-Related Depression; Perimenopausal Women", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06982677", "url": "https://clinicaltrials.gov/study/NCT06982677", "title": "Improving Outcomes in Early Menopause After Cancer", "sponsor": "Duke University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-01-20", "primary_completion": "2027-05 (est.)", "enrollment": 117, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-05-14", "first_posted": "2025-05-21", "results_posted": "", "conditions": "Early Menopause; Cancer; Premature Menopause; Surgical Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "EU CTIS", "id": "2023-506211-18-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2023-506211-18-00", "title": "PROPOSE: Effect of Intravaginal Prasterone on Genitourinary Syndrome in Women in Menopause with previous Breast Cancer or currently under treatment with endocrine therapy for Breast Cancer with aromatase inhibitor +/- LHRHa", "sponsor": "Istituto Europeo Di Oncologia S.r.l.", "sponsor_class": "Hospital/Clinic/Other health care facility", "phase": "Therapeutic confirmatory (Phase III)", "study_type": "Interventional", "status_code": 4, "status": "Ongoing, recruiting", "open": true, "start": "2025-01-09", "primary_completion": "", "enrollment": "95", "enrollment_type": "Planned", "countries": [ "Italy" ], "sex": "Female", "last_update": "2026-05-14", "first_posted": "2024-07-26", "results_posted": "", "conditions": "Postmenopausal women with previous breast cancer or currently under anti-oesterogenic therapy (aromatase inhibitor +/- LHRH analogue) presenting vulvar, vaginal or urinary bothersome symptoms (genitourinary syndrome).", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT07584109", "url": "https://clinicaltrials.gov/study/NCT07584109", "title": "The Effect of Value Clarification Based on Meleis's Transition Theory on Menopausal Symptoms, Depression, Anxiety, Stress, and Quality of Life in Perimenopausal Women", "sponsor": "Ordu University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-05-04 (est.)", "primary_completion": "2026-08-04 (est.)", "enrollment": 88, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-05-13", "first_posted": "2026-05-13", "results_posted": "", "conditions": "Menopausal Women", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07580846", "url": "https://clinicaltrials.gov/study/NCT07580846", "title": "ATENEA Study: Adherence to Creatine-Based Nutritional Supplementation in Estrogen-Depleted Women", "sponsor": "Margan Biotech", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-20", "primary_completion": "2026-10-01 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-05-12", "first_posted": "2026-05-12", "results_posted": "", "conditions": "Menopause; Estrogen Deficiency", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07577297", "url": "https://clinicaltrials.gov/study/NCT07577297", "title": "Comparative Effects of Kinesio Taping on Cervical Pain in Climacteric Women", "sponsor": "University of Valencia", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-05-20 (est.)", "primary_completion": "2026-09-01 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-05-11", "first_posted": "2026-05-11", "results_posted": "", "conditions": "Climacteric Women; Nonspecific Cervical Pain", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07341087", "url": "https://clinicaltrials.gov/study/NCT07341087", "title": "Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial", "sponsor": "King's College London", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-28", "primary_completion": "2027-11-01 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-05-08", "first_posted": "2026-01-14", "results_posted": "", "conditions": "Skin Inflammation; Immunosenescence; Inflammation; Skin Health; Eczema; Rosacea; Acne; Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT05251324", "url": "https://clinicaltrials.gov/study/NCT05251324", "title": "The Cardiovascular Impact of Hot Flushes", "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2022-03-01", "primary_completion": "2027-05-26 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-05-07", "first_posted": "2022-02-22", "results_posted": "", "conditions": "Hot Flashes; Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07572981", "url": "https://clinicaltrials.gov/study/NCT07572981", "title": "Study of the Effectiveness of Clinical Hypnosis and Self-hypnosis in Relieving Hot Flashes in Menopausal Women", "sponsor": "University Hospital, Toulouse", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-06-01 (est.)", "primary_completion": "2026-12-31 (est.)", "enrollment": 94, "enrollment_type": "Estimated", "countries": [ "France" ], "sex": "Female", "last_update": "2026-05-07", "first_posted": "2026-05-07", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07406412", "url": "https://clinicaltrials.gov/study/NCT07406412", "title": "Hormonal Regulation of Cardiometabolic Health Study", "sponsor": "University of Jyvaskyla", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-02-13", "primary_completion": "2028-12-15 (est.)", "enrollment": 120, "enrollment_type": "Estimated", "countries": [ "Finland" ], "sex": "Female", "last_update": "2026-05-06", "first_posted": "2026-02-12", "results_posted": "", "conditions": "Menopause Surgical", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07570732", "url": "https://clinicaltrials.gov/study/NCT07570732", "title": "Occupational Disruption and Role Strain During Perimenopause", "sponsor": "Russell Sage College", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-06-01 (est.)", "primary_completion": "2026-12-01 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-05-06", "first_posted": "2026-05-06", "results_posted": "", "conditions": "Perimenopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07563621", "url": "https://clinicaltrials.gov/study/NCT07563621", "title": "Determining the Extent of the Genitourinary Syndrome of Menopause Burden in Breast Cancer Survivors", "sponsor": "Jessa Hospital", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-05", "primary_completion": "2028-03-06 (est.)", "enrollment": 264, "enrollment_type": "Estimated", "countries": [ "Belgium" ], "sex": "Female", "last_update": "2026-05-04", "first_posted": "2026-05-04", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause (GSM); Breast Cancer; Vulvovaginal Atrophy; Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07500922", "url": "https://clinicaltrials.gov/study/NCT07500922", "title": "Menopause Effects on Cortico-reticular Functioning", "sponsor": "University of Jyvaskyla", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-25", "primary_completion": "2027-12-31 (est.)", "enrollment": 20, "enrollment_type": "Estimated", "countries": [ "Finland" ], "sex": "Female", "last_update": "2026-05-01", "first_posted": "2026-03-30", "results_posted": "", "conditions": "Menopause; Hormone Replacement Therapy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT05331209", "url": "https://clinicaltrials.gov/study/NCT05331209", "title": "Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers", "sponsor": "Shaare Zedek Medical Center", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-12-01 (est.)", "primary_completion": "2028-12-31 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [ "Israel" ], "sex": "Female", "last_update": "2026-04-29", "first_posted": "2022-04-15", "results_posted": "", "conditions": "Hot Flashes; Menopause Surgical", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06873971", "url": "https://clinicaltrials.gov/study/NCT06873971", "title": "Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause", "sponsor": "University of Nove de Julho", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-12-10", "primary_completion": "2026-11-10 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "Brazil" ], "sex": "Female", "last_update": "2026-04-23", "first_posted": "2025-03-13", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07284082", "url": "https://clinicaltrials.gov/study/NCT07284082", "title": "The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women", "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-04-17", "primary_completion": "2030-03-01 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-04-22", "first_posted": "2025-12-16", "results_posted": "", "conditions": "HIV; Menopause; Cardiovascular (CV) Risk; Carotid Arteriosclerosis; Body Composition", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07538167", "url": "https://clinicaltrials.gov/study/NCT07538167", "title": "Food Trial Evaluating Fecal Abundance of SBD111 With Once-Daily Versus Twice-Daily Administration in Healthy Adults", "sponsor": "Solarea Bio, Inc", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-04 (est.)", "primary_completion": "2027-01 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [], "sex": "All", "last_update": "2026-04-20", "first_posted": "2026-04-20", "results_posted": "", "conditions": "Osteopenia; Osteoporosis; Menopause Related Conditions; Probiotic Intervention; Synbiotics", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07131215", "url": "https://clinicaltrials.gov/study/NCT07131215", "title": "Smart Technology-Based Intervention and Monitoring of Physical and Mental Health in Early Postmenopausal Women", "sponsor": "YI-JU TSAI", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-08-15", "primary_completion": "2028-07-30 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "Taiwan" ], "sex": "Female", "last_update": "2026-04-14", "first_posted": "2025-08-20", "results_posted": "", "conditions": "Postmenopausal; Postmenopausal Disorder; Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07402382", "url": "https://clinicaltrials.gov/study/NCT07402382", "title": "Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women", "sponsor": "Nutrition 21, Inc.", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-11-01", "primary_completion": "2026-06-30 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-04-13", "first_posted": "2026-02-11", "results_posted": "", "conditions": "Glucose Monitoring, Continuous; Whole Body Protein Metabolism; Peri-menopausal Women; Post-menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06962345", "url": "https://clinicaltrials.gov/study/NCT06962345", "title": "Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs.", "sponsor": "Mucosa Innovations, S.L.", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-01-08", "primary_completion": "2026-12 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-03-30", "first_posted": "2025-05-08", "results_posted": "", "conditions": "Vulvar Atrophy; Vulvovaginal Signs and Symptoms; Genitourinary Syndrome of Menopause; Quality of Life; Menopause Related Conditions; Dyspareunia; Urinary Incontinence, Urgency-frequency; Sexual Function; Women\u00b4s Health; Vaginal Dryness", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07501377", "url": "https://clinicaltrials.gov/study/NCT07501377", "title": "Effects of a 6-months Fiber- and Polyphenol-rich Diet on Brain Inflammatory Processes in Perimenopausal Women Living With Overweight or Obesity", "sponsor": "Max Planck Institute for Human Cognitive and Brain Sciences", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-19", "primary_completion": "2029-06-30 (est.)", "enrollment": 120, "enrollment_type": "Estimated", "countries": [ "Germany" ], "sex": "Female", "last_update": "2026-03-30", "first_posted": "2026-03-30", "results_posted": "", "conditions": "Overweight and/or Obesity; Perimenopausal Women", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07497191", "url": "https://clinicaltrials.gov/study/NCT07497191", "title": "AMH Dynamic Changes to Predict Ovarian Reserve in Perimenopausal Breast Cancer", "sponsor": "Shengjing Hospital", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-03-05 (est.)", "primary_completion": "2029-03-05 (est.)", "enrollment": 300, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-03-27", "first_posted": "2026-03-27", "results_posted": "", "conditions": "Breast Cancer; Perimenopause; Ovarian Reserve", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07420218", "url": "https://clinicaltrials.gov/study/NCT07420218", "title": "Menopausal Hormones and Sympathetic Activation", "sponsor": "University of Delaware", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09-01 (est.)", "primary_completion": "2030-06-01 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-03-27", "first_posted": "2026-02-19", "results_posted": "", "conditions": "Perimenopausal Women", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07135232", "url": "https://clinicaltrials.gov/study/NCT07135232", "title": "The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health.", "sponsor": "Leeds Beckett University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-01 (est.)", "primary_completion": "2027-03-01 (est.)", "enrollment": 72, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-03-27", "first_posted": "2025-08-22", "results_posted": "", "conditions": "Perimenopause; Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07496294", "url": "https://clinicaltrials.gov/study/NCT07496294", "title": "Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy", "sponsor": "Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-04 (est.)", "primary_completion": "2027-10 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-03-27", "first_posted": "2026-03-27", "results_posted": "", "conditions": "Menopausal Women; Menopausal Symptom Relief; Hormone Therapy; Menopausal Hormone Therapy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07472881", "url": "https://clinicaltrials.gov/study/NCT07472881", "title": "Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women", "sponsor": "Chang Gung Memorial Hospital", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-03-16", "primary_completion": "2029-01-24 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "Taiwan" ], "sex": "Female", "last_update": "2026-03-20", "first_posted": "2026-03-16", "results_posted": "", "conditions": "Menopause; Perimenopause; Obesity; Overweight", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06318403", "url": "https://clinicaltrials.gov/study/NCT06318403", "title": "Estradiol Supplementation and Rotator Cuff Repair", "sponsor": "University of Utah", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2028-03 (est.)", "primary_completion": "2030-12 (est.)", "enrollment": 58, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-03-19", "first_posted": "2024-03-19", "results_posted": "", "conditions": "Rotator Cuff Tears; Rotator Cuff Injuries; Rotator Cuff Syndrome; Menopause Related Conditions; Menopause", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT07294339", "url": "https://clinicaltrials.gov/study/NCT07294339", "title": "A Randomized Controlled Trial of Acupuncture for the Management of Hot Flashes in Patients With Hormone Receptor-Positive Breast Cancer", "sponsor": "Peking University People's Hospital", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-04-01 (est.)", "primary_completion": "2027-08-01 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "China" ], "sex": "Female", "last_update": "2026-03-19", "first_posted": "2025-12-19", "results_posted": "", "conditions": "Acupuncture Treatment; Hormone Receptor-Positive Breast Cancer; Hot Flashes", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07481513", "url": "https://clinicaltrials.gov/study/NCT07481513", "title": "Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women", "sponsor": "American University of Beirut Medical Center", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-09-23", "primary_completion": "2026-06 (est.)", "enrollment": 140, "enrollment_type": "Estimated", "countries": [ "Lebanon" ], "sex": "Female", "last_update": "2026-03-19", "first_posted": "2026-03-19", "results_posted": "", "conditions": "Mental Health; Perimenopause; Intermittent Fasting", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07229976", "url": "https://clinicaltrials.gov/study/NCT07229976", "title": "Clinical Efficacy of Thumbtack Needle for Chronic Insomnia in Perimenopausal and Menopausal Women", "sponsor": "Huazhong University of Science and Technology", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-03-20 (est.)", "primary_completion": "2029-12-30 (est.)", "enrollment": 198, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-03-17", "first_posted": "2025-11-17", "results_posted": "", "conditions": "Chronic Insomnia During Perimenopause and Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07393672", "url": "https://clinicaltrials.gov/study/NCT07393672", "title": "Effects of Hemp-Derived Cannabinoids on Menopause Symptoms", "sponsor": "Washington State University", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-02-11", "primary_completion": "2026-11-10 (est.)", "enrollment": 104, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-03-10", "first_posted": "2026-02-06", "results_posted": "", "conditions": "Menopause; Perimenopause", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT01530373", "url": "https://clinicaltrials.gov/study/NCT01530373", "title": "Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients", "sponsor": "University of Arkansas", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2012-02", "primary_completion": "2027-07 (est.)", "enrollment": 110, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-03-05", "first_posted": "2012-02-09", "results_posted": "", "conditions": "Hot Flashes; Breast Cancer", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT07447947", "url": "https://clinicaltrials.gov/study/NCT07447947", "title": "Lived Experience and Perceptions of Menopause Among Patients Participating in the Multidisciplinary Care Pathways at Paris Saint-Joseph Hospital", "sponsor": "Fondation H\u00f4pital Saint-Joseph", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-05 (est.)", "primary_completion": "2026-11 (est.)", "enrollment": 24, "enrollment_type": "Estimated", "countries": [ "France" ], "sex": "Female", "last_update": "2026-03-04", "first_posted": "2026-03-04", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07441109", "url": "https://clinicaltrials.gov/study/NCT07441109", "title": "Shatavari Root Extract for Perimenopausal Symptoms", "sponsor": "SF Research Institute, Inc.", "sponsor_class": "NETWORK", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-03-11 (est.)", "primary_completion": "2026-06-15 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-03-03", "first_posted": "2026-02-27", "results_posted": "", "conditions": "Perimenopause; Women Health", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07443644", "url": "https://clinicaltrials.gov/study/NCT07443644", "title": "Targeting Insomnia to Prevent Depression in the Menopause Transition", "sponsor": "SRI International", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-09 (est.)", "primary_completion": "2031-02 (est.)", "enrollment": 230, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-03-02", "first_posted": "2026-03-02", "results_posted": "", "conditions": "Insomnia; Menopause Related Conditions", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07435545", "url": "https://clinicaltrials.gov/study/NCT07435545", "title": "Effect of Laughter Yoga on Menopausal Symptoms, Sleep, and Quality of Life in Menopausal Women", "sponsor": "Saglik Bilimleri Universitesi", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-03-01 (est.)", "primary_completion": "2026-03-29 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-03-02", "first_posted": "2026-02-27", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07254429", "url": "https://clinicaltrials.gov/study/NCT07254429", "title": "COMPASS - COpenhagen MenoPAuSe Study", "sponsor": "Martin Blomberg Jensen", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-10-02", "primary_completion": "2027-12 (est.)", "enrollment": 192, "enrollment_type": "Estimated", "countries": [ "Denmark" ], "sex": "Female", "last_update": "2026-03-02", "first_posted": "2025-11-28", "results_posted": "", "conditions": "Menopausal Osteoporosis; Bone Markers", "flags": [], "phase_group": "Phase 2" }, { "registry": "EU CTIS", "id": "2023-507782-25-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2023-507782-25-00", "title": "Efficacy of endothelin receptor antagonism in treatment of coronary artery spasm: a randomized controlled clinical trial.", "sponsor": "Stichting Radboud University Medical Center", "sponsor_class": "Hospital/Clinic/Other health care facility", "phase": "Phase II and Phase III (Integrated)", "study_type": "Interventional", "status_code": 4, "status": "Ongoing, recruiting", "open": true, "start": "2024-09-27", "primary_completion": "", "enrollment": "100", "enrollment_type": "Planned", "countries": [ "Netherlands" ], "sex": "Female, Male", "last_update": "2026-02-25", "first_posted": "2024-04-16", "results_posted": "", "conditions": "Coronary vasomotor dysfunction (spasm), Coronary vasospasm", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT05672901", "url": "https://clinicaltrials.gov/study/NCT05672901", "title": "Silicone Gel vs. Estrogen Vaginal Cream for the Management of Genitourinary Syndrome of Menopause", "sponsor": "Stratpharma AG", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-04-04", "primary_completion": "2026-09 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-02-20", "first_posted": "2023-01-05", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT05953090", "url": "https://clinicaltrials.gov/study/NCT05953090", "title": "VALOR: Vaginal Atrophy & Long-term Observation of Recovery", "sponsor": "Stratpharma AG", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-10-30", "primary_completion": "2028-06 (est.)", "enrollment": 2000, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-02-20", "first_posted": "2023-07-19", "results_posted": "", "conditions": "Atrophic Vaginitis; Vaginal Atrophy; Genitourinary Syndrome of Menopause; Lichen Sclerosus of Vulva; Lichen Planus of Vulva; Lichen Simplex of Vulva (Disorder)", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07423143", "url": "https://clinicaltrials.gov/study/NCT07423143", "title": "Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention", "sponsor": "Ume\u00e5 University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-03 (est.)", "primary_completion": "2029-02 (est.)", "enrollment": 2100, "enrollment_type": "Estimated", "countries": [ "Sweden" ], "sex": "Female", "last_update": "2026-02-20", "first_posted": "2026-02-20", "results_posted": "", "conditions": "Menopause; Opportunistic Salpingectomy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07419542", "url": "https://clinicaltrials.gov/study/NCT07419542", "title": "Effect of High Power Laser Acupuncture on Post Menopausal Hot Flashes", "sponsor": "Cairo University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-02-20 (est.)", "primary_completion": "2026-04-20 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2026-02-19", "first_posted": "2026-02-19", "results_posted": "", "conditions": "Hot Flashes", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07417709", "url": "https://clinicaltrials.gov/study/NCT07417709", "title": "Interest of Adaptated Physical Activity (APA) on the K Recovery Constant, Reflecting the Rate of Muscle Oxygenation Recovery in Menopausal Women Suffering From Depression", "sponsor": "Centre Hospitalier Universitaire de Besancon", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-02 (est.)", "primary_completion": "2028-10 (est.)", "enrollment": 52, "enrollment_type": "Estimated", "countries": [ "France" ], "sex": "Female", "last_update": "2026-02-18", "first_posted": "2026-02-18", "results_posted": "", "conditions": "Depression - Major Depressive Disorder; Menopausal Depression", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07419035", "url": "https://clinicaltrials.gov/study/NCT07419035", "title": "Bipolar Radiofrequency for Genitourinary Syndrome of Menopause", "sponsor": "University of Castilla-La Mancha", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-03-15 (est.)", "primary_completion": "2026-09-30 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-02-18", "first_posted": "2026-02-18", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause (GSM)", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06691178", "url": "https://clinicaltrials.gov/study/NCT06691178", "title": "Vaginal Changes After CO2 Laser", "sponsor": "University of California, Irvine", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-05-01", "primary_completion": "2027-05-01 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-02-18", "first_posted": "2024-11-15", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07417228", "url": "https://clinicaltrials.gov/study/NCT07417228", "title": "The Impact of Concurrent Training on Women Experiencing Symptoms of Menopause", "sponsor": "University College Dublin", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-12-12", "primary_completion": "2027-12-01 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "Ireland" ], "sex": "Female", "last_update": "2026-02-18", "first_posted": "2026-02-18", "results_posted": "", "conditions": "Menopause Symptoms", "flags": [ "Ireland" ], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07413705", "url": "https://clinicaltrials.gov/study/NCT07413705", "title": "BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women", "sponsor": "BTL Industries Ltd.", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-11-20", "primary_completion": "2026-12-11 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "Canada", "United States" ], "sex": "Female", "last_update": "2026-02-17", "first_posted": "2026-02-17", "results_posted": "", "conditions": "Depressive Symptoms; Urinary Incontinence; Sexual Dysfunction", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "EU CTIS", "id": "2023-507847-13-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2023-507847-13-00", "title": "A randomized intrapatient cross-over study to assess the efficacy of oxybutynin versus venlafaxine in REDucing hot FLASHes in women using endocrine therapy after breast cancer: the RED FLASH study.", "sponsor": "Reinier de Graaf Groep", "sponsor_class": "Hospital/Clinic/Other health care facility", "phase": "Therapeutic confirmatory (Phase III)", "study_type": "Interventional", "status_code": 4, "status": "Ongoing, recruiting", "open": true, "start": "2024-08-09", "primary_completion": "", "enrollment": "67", "enrollment_type": "Planned", "countries": [ "Netherlands" ], "sex": "Female", "last_update": "2026-02-16", "first_posted": "2024-04-09", "results_posted": "", "conditions": "Breast cancer", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06965686", "url": "https://clinicaltrials.gov/study/NCT06965686", "title": "Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk", "sponsor": "University of Chicago", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-01-31", "primary_completion": "2026-12-30 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-02-05", "first_posted": "2025-05-11", "results_posted": "", "conditions": "Menopausal; Dementia", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07165964", "url": "https://clinicaltrials.gov/study/NCT07165964", "title": "Nursing Interventions to Enhance Positive Mental Health and Self Care in Women During the Climacteric", "sponsor": "University of Barcelona", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-31", "primary_completion": "2026-07-01 (est.)", "enrollment": 250, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2026-02-05", "first_posted": "2025-09-10", "results_posted": "", "conditions": "Climacteric Symptoms; Climactericum; Self Care", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07120997", "url": "https://clinicaltrials.gov/study/NCT07120997", "title": "Prunes Preventing Bone Loss in Perimenopause", "sponsor": "Penn State University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-12-11", "primary_completion": "2029-09 (est.)", "enrollment": 124, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-02-04", "first_posted": "2025-08-13", "results_posted": "", "conditions": "Perimenopausal Bone Loss", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07376395", "url": "https://clinicaltrials.gov/study/NCT07376395", "title": "Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal Women", "sponsor": "Istanbul University - Cerrahpasa", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-02 (est.)", "primary_completion": "2027-08 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2026-02-03", "first_posted": "2026-01-29", "results_posted": "", "conditions": "Quality of Life; Depression; Anxiety; Stress", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07378787", "url": "https://clinicaltrials.gov/study/NCT07378787", "title": "Time-Restricted Eating in Combination With a Low Glycaemic Index Diet on Cognitive Function, Biological Ageing and Metabolic Health in Perimenopause and Menopause.", "sponsor": "University of Nicosia", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-01-17", "primary_completion": "2029-01-20 (est.)", "enrollment": 72, "enrollment_type": "Estimated", "countries": [ "Croatia", "Cyprus" ], "sex": "Female", "last_update": "2026-01-30", "first_posted": "2026-01-30", "results_posted": "", "conditions": "Late-perimenopause; Menopause; Perimenopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07375732", "url": "https://clinicaltrials.gov/study/NCT07375732", "title": "Transcranial Electrical Stimulation for Noninvasive Study of Menopausal/Perimenopausal Symptoms", "sponsor": "Carnegie Mellon University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-02 (est.)", "primary_completion": "2026-12 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-01-29", "first_posted": "2026-01-29", "results_posted": "", "conditions": "Menopausal Depression; Menopause Hot Flashes; Menopause; Menopause Related Conditions", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06855784", "url": "https://clinicaltrials.gov/study/NCT06855784", "title": "Time-Restricted Eating in Menopause and HOrmone-sensitive Breast Cancers (TREMHO)", "sponsor": "University Hospital, Geneva", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-04-30", "primary_completion": "2027-03-01 (est.)", "enrollment": 84, "enrollment_type": "Estimated", "countries": [ "Switzerland" ], "sex": "Female", "last_update": "2026-01-27", "first_posted": "2025-03-04", "results_posted": "", "conditions": "Menopause; Obesity and Overweight", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06446869", "url": "https://clinicaltrials.gov/study/NCT06446869", "title": "Menopausal Symptoms Probiotic Study", "sponsor": "Community Pharmacology Services Ltd", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-09-10", "primary_completion": "2026-07-25 (est.)", "enrollment": 140, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2026-01-26", "first_posted": "2024-06-06", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07356479", "url": "https://clinicaltrials.gov/study/NCT07356479", "title": "Enhancing Mental and Physical Health of Women Veterans 3.0", "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-10-01 (est.)", "primary_completion": "2030-09-30 (est.)", "enrollment": 18, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "All", "last_update": "2026-01-21", "first_posted": "2026-01-21", "results_posted": "", "conditions": "Cardiovascular Diseases; Overweight; Obesity; Hypertension; Cholesterol; Diabetes Mellitus; Prediabetic State; Menopause; Cognitive Behavioral Therapy; Primary Health Care; Stress Disorders, Post-Traumatic; Prevention; Implementation Science; Quality Improvement", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06999317", "url": "https://clinicaltrials.gov/study/NCT06999317", "title": "CARAMEL: Retrospective Study for Personalized Risk Assessment of Cardiovascular Disease in Menopausal and Perimenopausal Women Using Real World Data", "sponsor": "Hospital Universitario Virgen Macarena", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-03-01 (est.)", "primary_completion": "2027-12-01 (est.)", "enrollment": 1500000, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-01-15", "first_posted": "2025-05-31", "results_posted": "", "conditions": "Cardiovascular Risk Factors; Menopausal Women; Perimenopausal Women; Real World Data", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07342400", "url": "https://clinicaltrials.gov/study/NCT07342400", "title": "A Clinical Study to Assess Histological Changes From Treatment of Poly L-lactic Acid Biostimulator on Women at Various Menopausal Stages", "sponsor": "Galderma R&D", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-08-12", "primary_completion": "2026-11 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-01-15", "first_posted": "2026-01-15", "results_posted": "", "conditions": "Cheek Wrinkles; Menopausal Women", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06497894", "url": "https://clinicaltrials.gov/study/NCT06497894", "title": "No More Sleepless Nights in Perimenopause", "sponsor": "Insel Gruppe AG, University Hospital Bern", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-01-01", "primary_completion": "2026-07-01 (est.)", "enrollment": 54, "enrollment_type": "Estimated", "countries": [ "Switzerland" ], "sex": "Female", "last_update": "2026-01-13", "first_posted": "2024-07-12", "results_posted": "", "conditions": "Insomnia; Menopause", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT04439370", "url": "https://clinicaltrials.gov/study/NCT04439370", "title": "Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women", "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2019-10-01", "primary_completion": "2026-12-30 (est.)", "enrollment": 160, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2026-01-08", "first_posted": "2020-06-19", "results_posted": "", "conditions": "Hypertension; Menopause, Premature; Menopause; Blood Pressure", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07322250", "url": "https://clinicaltrials.gov/study/NCT07322250", "title": "The Effect of Blood Flow Restriction Training on Postmenopausal Stress Urinary Incontinence", "sponsor": "Kafrelsheikh University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-12-30 (est.)", "primary_completion": "2026-06-15 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2026-01-07", "first_posted": "2026-01-07", "results_posted": "", "conditions": "Post Menopausal Stress Urinary Incontinence", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07309692", "url": "https://clinicaltrials.gov/study/NCT07309692", "title": "Different Modalities for the Evaluation of Patients With Peri-menopausal Bleeding", "sponsor": "Sohag University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-12-01", "primary_completion": "2026-08-31 (est.)", "enrollment": 106, "enrollment_type": "Estimated", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2025-12-30", "first_posted": "2025-12-30", "results_posted": "", "conditions": "Perimenopausal Bleeding", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06343870", "url": "https://clinicaltrials.gov/study/NCT06343870", "title": "Estradiol and Testosterone Subdermal Implants for Menopause Treatment (ESTIME)", "sponsor": "University of Sao Paulo General Hospital", "sponsor_class": "OTHER", "phase": "Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-12-18", "primary_completion": "2026-08-18 (est.)", "enrollment": 140, "enrollment_type": "Estimated", "countries": [ "Brazil" ], "sex": "Female", "last_update": "2025-12-29", "first_posted": "2024-04-03", "results_posted": "", "conditions": "Menopause; Testosterone Deficiency; Estrogen Deficiency", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT07299903", "url": "https://clinicaltrials.gov/study/NCT07299903", "title": "IMB-Based Sleep Hygiene Education for Menopausal Women: Effects on Sleep Quality and Depression", "sponsor": "Ankara Yildirim Beyaz\u0131t University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2026-01-01 (est.)", "primary_completion": "2026-03-01 (est.)", "enrollment": 500, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2025-12-23", "first_posted": "2025-12-23", "results_posted": "", "conditions": "Insomnia; Depressive Symptoms", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07251296", "url": "https://clinicaltrials.gov/study/NCT07251296", "title": "Impact of Funcional Exercise and Supplementation in Perimenopausal Women's Health", "sponsor": "University of Valencia", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-12-15", "primary_completion": "2026-07 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2025-12-22", "first_posted": "2025-11-26", "results_posted": "", "conditions": "Perimenopause; Aging", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07259525", "url": "https://clinicaltrials.gov/study/NCT07259525", "title": "Escitalopram Plasma Concentrations in Premenopausal and Postmenopausal Women", "sponsor": "Eskisehir Osmangazi University", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2026-01 (est.)", "primary_completion": "2028-01 (est.)", "enrollment": 94, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2025-12-22", "first_posted": "2025-12-02", "results_posted": "", "conditions": "Therapeutic Drug Monitoring (TDM); Menopause; Depression - Major Depressive Disorder; General Anxiety Disorder", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07292857", "url": "https://clinicaltrials.gov/study/NCT07292857", "title": "Comparing and Predicting the Risk of Respiratory Tract Infection (RTI) Among Post-menopausal Women on or Without Hormone Replacement Therapy (HRT): an Observational Cohort Study", "sponsor": "Insel Gruppe AG, University Hospital Bern", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-09-18", "primary_completion": "2025-12 (est.)", "enrollment": 400, "enrollment_type": "Estimated", "countries": [ "Switzerland" ], "sex": "Female", "last_update": "2025-12-18", "first_posted": "2025-12-18", "results_posted": "", "conditions": "Menopausal Women; Respiratory Tract Infections (RTI)", "flags": [], "phase_group": "Observational" }, { "registry": "EU CTIS", "id": "2025-523214-83-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2025-523214-83-00", "title": "The effect of transdermal 17-\u03b2-estradiol/progesterone supplementation on glucose regulation in peri- and postmenopausal women with type 1 and type 2 diabetes", "sponsor": "Amsterdam UMC Stichting", "sponsor_class": "Patient organisation/association", "phase": "Therapeutic use (Phase IV)", "study_type": "Interventional", "status_code": 4, "status": "Ongoing, recruiting", "open": true, "start": "2026-02-09", "primary_completion": "", "enrollment": "48", "enrollment_type": "Planned", "countries": [ "Netherlands" ], "sex": "Female", "last_update": "2025-12-15", "first_posted": "2025-12-15", "results_posted": "", "conditions": "Diabetes Mellitus, (peri) Menopause", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT06376812", "url": "https://clinicaltrials.gov/study/NCT06376812", "title": "No Time to Pause: Physical Activity to Improve Health of Midlife Hispanic Women", "sponsor": "The University of Texas Medical Branch, Galveston", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2027-01-20 (est.)", "primary_completion": "2029-01 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-12-08", "first_posted": "2024-04-19", "results_posted": "", "conditions": "Elevated Blood Pressure; Perimenopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07112651", "url": "https://clinicaltrials.gov/study/NCT07112651", "title": "Efficacy of CL25216 on Vasomotor Symptoms in Women During Perimenopause", "sponsor": "ApexCPG LLC", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-11-24 (est.)", "primary_completion": "2026-06-12 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [ "India" ], "sex": "Female", "last_update": "2025-12-05", "first_posted": "2025-08-08", "results_posted": "", "conditions": "Vasomotor Symptoms", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07238478", "url": "https://clinicaltrials.gov/study/NCT07238478", "title": "JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women", "sponsor": "Bonafide Health", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-05-14", "primary_completion": "2026-07 (est.)", "enrollment": 250, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-11-20", "first_posted": "2025-11-20", "results_posted": "", "conditions": "Joint Discomfort; Joint Pain, Stiffness, Function; Joint Pain; Hot Flashes; Hot Flash; Night Sweats; Vasomotor Symptoms", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07052279", "url": "https://clinicaltrials.gov/study/NCT07052279", "title": "Water Based Burpee Exercises on Functional Capacity in Poste-menopausal Women After Thyroidectomy", "sponsor": "Al-Zaytoonah University of Jordan", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-09-01", "primary_completion": "2025-11-20 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2025-11-19", "first_posted": "2025-07-04", "results_posted": "", "conditions": "Burpee Exercise; Water Exercises; Functional Capacity; Postmenopausal; Thyroidectomy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06347926", "url": "https://clinicaltrials.gov/study/NCT06347926", "title": "Study of Sexual Quality of Life in Women With Breast Cancer Who Had Multidisciplinary Management With Photobiomodulation for Genitourinary Syndrome of the Menopause", "sponsor": "Institut du Cancer de Montpellier - Val d'Aurelle", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-03-13", "primary_completion": "2027-12 (est.)", "enrollment": 25, "enrollment_type": "Estimated", "countries": [ "France" ], "sex": "Female", "last_update": "2025-11-18", "first_posted": "2024-04-04", "results_posted": "", "conditions": "Breast Cancer", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT05831709", "url": "https://clinicaltrials.gov/study/NCT05831709", "title": "The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women", "sponsor": "University Hospital, Ghent", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-05-12", "primary_completion": "2027-12-31 (est.)", "enrollment": 390, "enrollment_type": "Estimated", "countries": [ "Belgium" ], "sex": "Female", "last_update": "2025-11-18", "first_posted": "2023-04-26", "results_posted": "", "conditions": "Postmenopause; Menopausal Complaints", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "EU CTIS", "id": "2024-512071-12-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2024-512071-12-00", "title": "The role of online sleep intervention and hormone therapy on sleep, climacteric symptoms and mood in the perimenopause", "sponsor": "Amsterdam UMC Stichting", "sponsor_class": "Hospital/Clinic/Other health care facility", "phase": "Therapeutic use (Phase IV)", "study_type": "Interventional", "status_code": 4, "status": "Ongoing, recruiting", "open": true, "start": "2025-10-29", "primary_completion": "", "enrollment": "222", "enrollment_type": "Planned", "countries": [ "Netherlands" ], "sex": "Female", "last_update": "2025-10-22", "first_posted": "2025-03-21", "results_posted": "", "conditions": "Insomnia, Climacteric symptoms", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07210229", "url": "https://clinicaltrials.gov/study/NCT07210229", "title": "The Effectiveness of a Proprietary Ashwagandha Extract on Menopausal Symptoms: A Three-Arm Randomized, Double-Blinded, Placebo Controlled Clinical Trial", "sponsor": "Nutraceuticals Research Institute", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-10-01 (est.)", "primary_completion": "2026-02-28 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-10-07", "first_posted": "2025-10-07", "results_posted": "", "conditions": "Menopausal Hot Flashes; Menopausal Women", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07022925", "url": "https://clinicaltrials.gov/study/NCT07022925", "title": "A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women", "sponsor": "IdentifyHer Limited", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-04", "primary_completion": "2025-10 (est.)", "enrollment": 110, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2025-09-18", "first_posted": "2025-06-15", "results_posted": "", "conditions": "Perimenopause; Perimenopausal Depression; Perimenopausal Insomnia; Perimenopausal Women; Menopausal Depression; Menopausal Hot Flashes; Menopausal and Postmenopausal Disorders; Menopausal Vasomotor Symptoms", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07160127", "url": "https://clinicaltrials.gov/study/NCT07160127", "title": "A Clinical Study of Chinese Herbal Formula TJAOA103 in Treating Genitourinary Syndrome of Menopause", "sponsor": "Tongji Hospital", "sponsor_class": "OTHER", "phase": "Early Phase 1", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-09-15 (est.)", "primary_completion": "2027-06-15 (est.)", "enrollment": 113, "enrollment_type": "Estimated", "countries": [ "China" ], "sex": "Female", "last_update": "2025-09-17", "first_posted": "2025-09-08", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause (GSM)", "flags": [], "phase_group": "Early Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT06787066", "url": "https://clinicaltrials.gov/study/NCT06787066", "title": "Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms", "sponsor": "University of Missouri-Columbia", "sponsor_class": "OTHER", "phase": "Early Phase 1", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-10", "primary_completion": "2026-12 (est.)", "enrollment": 75, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-09-15", "first_posted": "2025-01-22", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "Early Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT07034976", "url": "https://clinicaltrials.gov/study/NCT07034976", "title": "Efficacy of Non-ablative Radiofrequency Combined With Pelvic Floor Muscle Training for Genitourinary Syndrome of Menopause in Breast Cancer Survivors (RF-SGM)", "sponsor": "Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-09-01", "primary_completion": "2026-12-31 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2025-09-15", "first_posted": "2025-06-24", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause (GSM); Breast Cancer", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07151482", "url": "https://clinicaltrials.gov/study/NCT07151482", "title": "Impact of Oral Supplementation With Bioactive Collagen Peptides and Other Functional Ingredients", "sponsor": "Fondazione Policlinico Universitario Agostino Gemelli IRCCS", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-09-01 (est.)", "primary_completion": "2027-09-01 (est.)", "enrollment": 43, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2025-09-03", "first_posted": "2025-09-03", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07149285", "url": "https://clinicaltrials.gov/study/NCT07149285", "title": "Effect of Mandala Practice on Menopausal Symptoms and Quality of Life", "sponsor": "Emine Karacan", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-09 (est.)", "primary_completion": "2025-09 (est.)", "enrollment": 78, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2025-08-29", "first_posted": "2025-08-29", "results_posted": "", "conditions": "Menopause Symptom Management; Quality of Life; Menopausal Symptoms", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07146321", "url": "https://clinicaltrials.gov/study/NCT07146321", "title": "A Study to Investigate the Effect of a Multivitamin, Multi-nutrient Supplement on Mental and Emotional Wellbeing", "sponsor": "Biologica Inc", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-09-01 (est.)", "primary_completion": "2026-03-09 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-08-28", "first_posted": "2025-08-28", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07141953", "url": "https://clinicaltrials.gov/study/NCT07141953", "title": "Yoga in Women With Surgical Menopause After Gynecological Cancer", "sponsor": "Dokuz Eylul University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-09-01 (est.)", "primary_completion": "2026-01-01 (est.)", "enrollment": 46, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2025-08-26", "first_posted": "2025-08-26", "results_posted": "", "conditions": "Gynecological Oncology; Gynecology; Oncology; Surgical Menopause; Symptom Management; Quality of Life; Sleep Quality; Well-being; Yoga; Yoga for Cancer", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06306404", "url": "https://clinicaltrials.gov/study/NCT06306404", "title": "Sleeping Through Menopause", "sponsor": "VU University of Amsterdam", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-10-01 (est.)", "primary_completion": "2029-10-01 (est.)", "enrollment": 222, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2025-08-24", "first_posted": "2024-03-12", "results_posted": "", "conditions": "Menopause; Insomnia", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT07136220", "url": "https://clinicaltrials.gov/study/NCT07136220", "title": "A Pilot Study to Evaluate Equol and Its Effects on Menopausal Symptoms Experienced by Women in Singapore", "sponsor": "Ang Seng Bin", "sponsor_class": "OTHER_GOV", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-02", "primary_completion": "2025-12 (est.)", "enrollment": 300, "enrollment_type": "Estimated", "countries": [ "Singapore" ], "sex": "Female", "last_update": "2025-08-22", "first_posted": "2025-08-22", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07120542", "url": "https://clinicaltrials.gov/study/NCT07120542", "title": "Menopausal Impact on Skin Aging Among Egyptian Women", "sponsor": "Sohag University", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-11-01 (est.)", "primary_completion": "2026-11 (est.)", "enrollment": 500, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2025-08-13", "first_posted": "2025-08-13", "results_posted": "", "conditions": "Skin Aging", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07100639", "url": "https://clinicaltrials.gov/study/NCT07100639", "title": "Singapore Population Research on Integrated exposoMe & Early Menopause", "sponsor": "Institute for Human Development and Potential (IHDP), Singapore", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-08-06 (est.)", "primary_completion": "2028-03-31 (est.)", "enrollment": 400, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2025-08-03", "first_posted": "2025-08-03", "results_posted": "", "conditions": "Early Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06732843", "url": "https://clinicaltrials.gov/study/NCT06732843", "title": "Does Recombinant FSH (rFSH, i.g. Gonal F\u00ae) as Compared to Human Menopausal Gonadotrophin (hMG) Affect Telomere Length of Cumulus Cells During Antral Follicle Growth and Impact Blastocyst Status?", "sponsor": "ART Fertility Clinics LLC", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-23", "primary_completion": "2026-12-31 (est.)", "enrollment": 10, "enrollment_type": "Estimated", "countries": [ "United Arab Emirates" ], "sex": "Female", "last_update": "2025-07-25", "first_posted": "2024-12-13", "results_posted": "", "conditions": "OVARIAN STIMULATION; Telomere Length; Telomere Length, Mean Leukocyte", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT07034885", "url": "https://clinicaltrials.gov/study/NCT07034885", "title": "Effects of Mindfulness-Based Self-Efficacy Development Program on Postmenopausal Women", "sponsor": "Nurcan G\u00f6kg\u00f6z", "sponsor_class": "OTHER_GOV", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-09-15 (est.)", "primary_completion": "2026-01 (est.)", "enrollment": 70, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2025-07-22", "first_posted": "2025-06-24", "results_posted": "", "conditions": "Postmenopausal Period; Menopausal Symptoms; Quality of Life; Stress Management; Self-Efficacy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07070635", "url": "https://clinicaltrials.gov/study/NCT07070635", "title": "Abertay Tea for Cardiovascular Health During Menopause", "sponsor": "Abertay University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-06-16", "primary_completion": "2025-10 (est.)", "enrollment": 44, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2025-07-17", "first_posted": "2025-07-17", "results_posted": "", "conditions": "Cardiovascular Risk Factor; Vascular Function", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07033013", "url": "https://clinicaltrials.gov/study/NCT07033013", "title": "A Randomized, Double Blind, Placebo Controlled, Clinical Study to Examine the Benefits of an Oral Product in Panelists With Menopausal Symptoms Including Vasomotor Symptoms (VMS).", "sponsor": "Olly, PBC", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-07-07", "primary_completion": "2025-07-25 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-07-16", "first_posted": "2025-06-24", "results_posted": "", "conditions": "Healthy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07042737", "url": "https://clinicaltrials.gov/study/NCT07042737", "title": "The Effect of Animation-Based Education on Menopausal Women's Attitudes, Behaviors, and Screening Test Participation Regarding Breast Cancer", "sponsor": "Inonu University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-06-20 (est.)", "primary_completion": "2025-07-31 (est.)", "enrollment": 136, "enrollment_type": "Estimated", "countries": [ "Turkey (T\u00fcrkiye)" ], "sex": "Female", "last_update": "2025-06-29", "first_posted": "2025-06-29", "results_posted": "", "conditions": "Menopausal Women; Education Nursing; Breast Cancer Females; Motivation; Screening Strategy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT07021664", "url": "https://clinicaltrials.gov/study/NCT07021664", "title": "Health, Imaging, and Cognition Across the Menopausal Transition", "sponsor": "Universit\u00e9 de Sherbrooke", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-07-01 (est.)", "primary_completion": "2026-03-01 (est.)", "enrollment": 45, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2025-06-15", "first_posted": "2025-06-15", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "EU CTIS", "id": "2025-520741-68-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2025-520741-68-00", "title": "Genitourinary Syndrome and Female Sexual Dysfunction: Effect of\ntopical glyceryl trinitrate on female genital function in the peri- and postmenopause \u2013 a Pilot Study", "sponsor": "Medical University Of Vienna", "sponsor_class": "Educational Institution", "phase": "Human Pharmacology (Phase I)- Other", "study_type": "Interventional", "status_code": 2, "status": "Authorised, recruitment pending", "open": true, "start": "", "primary_completion": "", "enrollment": "32", "enrollment_type": "Planned", "countries": [ "Austria" ], "sex": "Female", "last_update": "2025-06-02", "first_posted": "2025-02-05", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT06644573", "url": "https://clinicaltrials.gov/study/NCT06644573", "title": "Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy\u2122 in Patients With Sleep Deprivation and Chronic Insomnia", "sponsor": "Nyree Penn", "sponsor_class": "INDUSTRY", "phase": "Phase 1", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-11-01 (est.)", "primary_completion": "2026-05-01 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "All", "last_update": "2025-05-28", "first_posted": "2024-10-16", "results_posted": "", "conditions": "Chronic Insomnia; Sleep Deprivation; REM Behavior Disorder; REM Sleep Behavior Disorder; REM Sleep Measurement; Insomnia; Insomnia Related to Specified Disorder; Insomnia Due to Other Mental Disorder; Insomnia Comorbid to Psychiatric Disorder; Insomnia Due to Anxiety and Fear; Insomnia Related to Another Mental Condition; Insomnia Disorders; Idiopathic Hypersomnia; Sleep Disorders, Circadian Rhythm; Post Trauma Nightmares; PTSD - Post Traumatic Stress Disorder; Sleep Quality; Anesthesia; Anxiety; Depression; Mental Health; Alzheimer Disease or Associated Disorder; Parkinsons; Circadian Rhythm; Circadian Dysregulation; PTSD; Post-Traumatic; Post-Traumatic Stress Disorder Complex; Military Combat Stress Reaction; Sleep; Military Activity; Veterans; Shift Work Sleep Disorder; Menopause Related Conditions; Pain; Cancer Pain; Athletes", "flags": [], "phase_group": "Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT06852755", "url": "https://clinicaltrials.gov/study/NCT06852755", "title": "Development of Biomarkers for Monitoring Menopause in Women", "sponsor": "Fu Jen Catholic University Hospital", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-07-30", "primary_completion": "2026-02 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Taiwan" ], "sex": "Female", "last_update": "2025-05-25", "first_posted": "2025-02-28", "results_posted": "", "conditions": "Perimenopausal Biomarkers; Mitochondrial Biomarkers", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06710002", "url": "https://clinicaltrials.gov/study/NCT06710002", "title": "Effectiveness of a Telerehabilitation Program for Improving Sexual Function and Reducing Pain in Menopausal Women", "sponsor": "Instituto M\u00e9dico Tecnol\u00f3gico SL", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-05-05", "primary_completion": "2026-03 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2025-05-23", "first_posted": "2024-11-29", "results_posted": "", "conditions": "Menopause; Genitourinary Syndrome of Menopause; Dyspareunia", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "EU CTIS", "id": "2024-520234-30-00", "url": "https://euclinicaltrials.eu/ctis-public/view/2024-520234-30-00", "title": "A randomized, double-blind, placebo-controlled, multicenter study evaluating the effect of a 12-week\nDHEA combination of 20 mg and 2 mg prolonged-release melatonin on sleep quality and mood in\npostmenopausal women.", "sponsor": "The Pharmaceutical Company LEK-AM Sp. Zoo., Przedsiebiorstwo Farmaceutyczne Lek-Am Sp. z o.o.", "sponsor_class": "Industry, Pharmaceutical company", "phase": "Therapeutic confirmatory (Phase III)", "study_type": "Interventional", "status_code": 4, "status": "Ongoing, recruiting", "open": true, "start": "2024-11-30", "primary_completion": "", "enrollment": "100", "enrollment_type": "Planned", "countries": [ "Poland" ], "sex": "Female", "last_update": "2025-05-13", "first_posted": "2025-01-30", "results_posted": "", "conditions": "Menopause, sleep disorders in the postmenopausal period", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT05483634", "url": "https://clinicaltrials.gov/study/NCT05483634", "title": "Compare Vaginal Estrogen and Platelet-rich Plasma Over Women With Genitourinary Syndrome of Menopause", "sponsor": "Mackay Memorial Hospital", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-12-01 (est.)", "primary_completion": "2026-12-31 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "Taiwan" ], "sex": "Female", "last_update": "2025-05-09", "first_posted": "2022-08-02", "results_posted": "", "conditions": "Menopause; Platelet-rich Plasma; Estrogen Replacement Therapy; Vaginal Atrophy", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06959745", "url": "https://clinicaltrials.gov/study/NCT06959745", "title": "Magnesium-L-Threonate Improves Menopausal Symptoms", "sponsor": "Guangdong Provincial People's Hospital", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-05-15 (est.)", "primary_completion": "2025-09-30 (est.)", "enrollment": 50, "enrollment_type": "Estimated", "countries": [ "China" ], "sex": "Female", "last_update": "2025-05-07", "first_posted": "2025-05-07", "results_posted": "", "conditions": "Menopause Syndrome; Magnesium", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06950463", "url": "https://clinicaltrials.gov/study/NCT06950463", "title": "EFFECT OF CIRCUIT TRAINING ON BONE MINERAL DENSITY IN POST MENOPAUSAL PERIOD", "sponsor": "Cairo University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-01-01", "primary_completion": "2025-06-01 (est.)", "enrollment": 44, "enrollment_type": "Estimated", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2025-04-30", "first_posted": "2025-04-30", "results_posted": "", "conditions": "Post Menopausal; Osteoporosis", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06721936", "url": "https://clinicaltrials.gov/study/NCT06721936", "title": "Genitourinary Syndrome of Menopause in Breast Cancer", "sponsor": "University of Alcala", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-11-29", "primary_completion": "2027-12-31 (est.)", "enrollment": 182, "enrollment_type": "Estimated", "countries": [ "Spain" ], "sex": "Female", "last_update": "2025-04-27", "first_posted": "2024-12-06", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause (GSM); Breast Cancer Female", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06939868", "url": "https://clinicaltrials.gov/study/NCT06939868", "title": "Effect of a Cepham Supplement on Hot Flashes and Menopausal Symptoms in Postmenopausal Women", "sponsor": "Jacksonville University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-05-01 (est.)", "primary_completion": "2025-08-30 (est.)", "enrollment": 44, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-04-23", "first_posted": "2025-04-23", "results_posted": "", "conditions": "D008593", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06899243", "url": "https://clinicaltrials.gov/study/NCT06899243", "title": "Efficacy of CL22205 on Bone Mineral Density and Menopausal Symptoms", "sponsor": "Eetho Brands, Inc", "sponsor_class": "INDUSTRY", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-03-25 (est.)", "primary_completion": "2026-05-10 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2025-03-27", "first_posted": "2025-03-27", "results_posted": "", "conditions": "Menopausal Symptoms", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT04305808", "url": "https://clinicaltrials.gov/study/NCT04305808", "title": "Characterization of Vaginal, Urinary and Fecal Microbiomes in Women with Recurrent Urinary Tract Infections", "sponsor": "Hadassah Medical Organization", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2021-08-01", "primary_completion": "2025-12-30 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "Israel" ], "sex": "Female", "last_update": "2025-03-19", "first_posted": "2020-03-12", "results_posted": "", "conditions": "Urinary Tract Infections; Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06222073", "url": "https://clinicaltrials.gov/study/NCT06222073", "title": "Getting Under the Skin of the Menopausal Hot Flush", "sponsor": "Liverpool John Moores University", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-01-01", "primary_completion": "2025-10-31 (est.)", "enrollment": 36, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2025-03-18", "first_posted": "2024-01-24", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06879938", "url": "https://clinicaltrials.gov/study/NCT06879938", "title": "Concomitant Treatment with Topical Hyaluronic Acid and High Concentration Oxygen Therapy (Vaginal Natural Oxygenation Device - VNOD) in the Improvement of Symptoms Related to Genitourinary Syndrome of Menopause in Women with Natural and Oncological Postmenopause: Open-Label, Single-Center, Randomize", "sponsor": "Fondazione IRCCS Policlinico San Matteo di Pavia", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-10-16", "primary_completion": "2025-12 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2025-03-17", "first_posted": "2025-03-17", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06874738", "url": "https://clinicaltrials.gov/study/NCT06874738", "title": "A Real-world Clinical Study on the Treatment of Menopausal Syndrome With Liuwei Dihuang Pills", "sponsor": "China Academy of Chinese Medical Sciences", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-03-08 (est.)", "primary_completion": "2026-12-30 (est.)", "enrollment": 1000, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2025-03-13", "first_posted": "2025-03-13", "results_posted": "", "conditions": "Menopausal Syndrome", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06865066", "url": "https://clinicaltrials.gov/study/NCT06865066", "title": "Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety", "sponsor": "Dr. Nazanin Alavi", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-11-11", "primary_completion": "2025-02-28 (est.)", "enrollment": 25, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2025-03-07", "first_posted": "2025-03-07", "results_posted": "", "conditions": "Menopause; Anxiety; Depressive/Anxiety Symptoms; Perimenopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06864520", "url": "https://clinicaltrials.gov/study/NCT06864520", "title": "Evaluation of the Beneficial Effects of a Product Containing \u0393-aminobutyric Acid (GABA) on Climacteric Syndrome Disorders", "sponsor": "Ospedale Policlinico San Martino", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-10-25", "primary_completion": "2025-11 (est.)", "enrollment": 112, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2025-03-07", "first_posted": "2025-03-07", "results_posted": "", "conditions": "Climacteric Symptoms; Hot Flashes", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06848829", "url": "https://clinicaltrials.gov/study/NCT06848829", "title": "Difference of Tear Ferning Between Women with and Without Menopausal.", "sponsor": "Chung Shan Medical University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-10-01", "primary_completion": "2025-09-01 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "Taiwan" ], "sex": "Female", "last_update": "2025-02-27", "first_posted": "2025-02-27", "results_posted": "", "conditions": "Dry Eye Syndromes", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06831890", "url": "https://clinicaltrials.gov/study/NCT06831890", "title": "Surrogating Physician-recorded SCORE2 Risk Calculator Inputs by Using Auxiliary Data", "sponsor": "Insel Gruppe AG, University Hospital Bern", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-08-24", "primary_completion": "2025-03 (est.)", "enrollment": 250, "enrollment_type": "Estimated", "countries": [ "Switzerland" ], "sex": "Female", "last_update": "2025-02-18", "first_posted": "2025-02-18", "results_posted": "", "conditions": "Cardiovascular Diseases; Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06798584", "url": "https://clinicaltrials.gov/study/NCT06798584", "title": "How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?", "sponsor": "Purdue University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-03-01 (est.)", "primary_completion": "2025-12 (est.)", "enrollment": 240, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2025-02-13", "first_posted": "2025-01-29", "results_posted": "", "conditions": "Iron Deficiency Anemia Treatment; Iron Deficiency; Iron Deficiency (Without Anemia)", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06808347", "url": "https://clinicaltrials.gov/study/NCT06808347", "title": "Difference in Serum Estrogen Level Based on Methods of Vaginal Estrogen Application (fingertip Vs Applicator Use) in Post-menopausal Women", "sponsor": "Walter Reed National Military Medical Center", "sponsor_class": "FED", "phase": "Phase 4", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-02-01 (est.)", "primary_completion": "2025-06-30 (est.)", "enrollment": 110, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2025-02-05", "first_posted": "2025-02-05", "results_posted": "", "conditions": "Postmenopausal Atrophic Vaginitis; Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT06806501", "url": "https://clinicaltrials.gov/study/NCT06806501", "title": "Muscle Mass, Quality, and the Menopause: Sex-specific Strategies to Mitigate Sarcopenia in Ageing Populations", "sponsor": "University of Nottingham", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-07-29", "primary_completion": "2026-03 (est.)", "enrollment": 18, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2025-02-04", "first_posted": "2025-02-04", "results_posted": "", "conditions": "Healthy", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06106529", "url": "https://clinicaltrials.gov/study/NCT06106529", "title": "REDucing Hot FLASHes in Women Using Endocrine Therapy.", "sponsor": "Reinier de Graaf Groep", "sponsor_class": "OTHER", "phase": "Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-10-03", "primary_completion": "2029-01-01 (est.)", "enrollment": 260, "enrollment_type": "Estimated", "countries": [ "Netherlands" ], "sex": "Female", "last_update": "2025-02-04", "first_posted": "2023-10-30", "results_posted": "", "conditions": "Breast Cancer; Hot Flash Due to Medication", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06030388", "url": "https://clinicaltrials.gov/study/NCT06030388", "title": "Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women", "sponsor": "Linkoeping University", "sponsor_class": "OTHER_GOV", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-09-12", "primary_completion": "2027-06 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "Sweden" ], "sex": "Female", "last_update": "2025-01-22", "first_posted": "2023-09-11", "results_posted": "", "conditions": "Postmenopausal Symptoms; Hot Flashes", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06704516", "url": "https://clinicaltrials.gov/study/NCT06704516", "title": "COmmencing Menopausal HOrmone Replacement Therapy and the Effect on Metabolic-dysfunction Associated Steatotic Liver Disease: a Pilot Mechanistic Study", "sponsor": "University of Oxford", "sponsor_class": "OTHER", "phase": "Phase 1", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2025-01 (est.)", "primary_completion": "2025-08-05 (est.)", "enrollment": 10, "enrollment_type": "Estimated", "countries": [ "United Kingdom" ], "sex": "Female", "last_update": "2025-01-13", "first_posted": "2024-11-26", "results_posted": "", "conditions": "Menopause; Metabolic Dysfunction Associated Steatotic Liver Disease", "flags": [], "phase_group": "Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT06768073", "url": "https://clinicaltrials.gov/study/NCT06768073", "title": "Intravaginal Negative Pressure Medical Device for Treatment of Genitourinary Syndrome of Menopause (GSM)", "sponsor": "AVeta Medical", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-03-03 (est.)", "primary_completion": "2025-11-03 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "Georgia", "United States" ], "sex": "Female", "last_update": "2025-01-10", "first_posted": "2025-01-10", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06750263", "url": "https://clinicaltrials.gov/study/NCT06750263", "title": "Effects of Balance Exercises With and Without Clamshell Exercises After Menopause", "sponsor": "Riphah International University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2024-12-15 (est.)", "primary_completion": "2025-04-15 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2024-12-27", "first_posted": "2024-12-27", "results_posted": "", "conditions": "Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06726746", "url": "https://clinicaltrials.gov/study/NCT06726746", "title": "Efficacy of Fractional CO2 Laser Treatment in Post-Menopausal Women With Vaginal Atrophy", "sponsor": "Cairo University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-10-01", "primary_completion": "2025-03-01 (est.)", "enrollment": 20, "enrollment_type": "Estimated", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2024-12-10", "first_posted": "2024-12-10", "results_posted": "", "conditions": "Post Menopausal Vaginal Atrophy", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06007027", "url": "https://clinicaltrials.gov/study/NCT06007027", "title": "Vaginal CO2 Laser Therapy for Genitourinary Syndrome in Breast Cancer Survivors", "sponsor": "University of Aarhus", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-12-01", "primary_completion": "2026-01-30 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "Denmark" ], "sex": "Female", "last_update": "2024-12-05", "first_posted": "2023-08-23", "results_posted": "", "conditions": "Genitourinary Syndrome of Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06716554", "url": "https://clinicaltrials.gov/study/NCT06716554", "title": "Efficacy and Safety of Shatavari for Treatment of Menopausal Symptoms in Women: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study", "sponsor": "SF Research Institute, Inc.", "sponsor_class": "NETWORK", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-10-26", "primary_completion": "2024-12-26 (est.)", "enrollment": 51, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2024-12-04", "first_posted": "2024-12-04", "results_posted": "", "conditions": "Menopause; Hot Flashes; Mood", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT04478305", "url": "https://clinicaltrials.gov/study/NCT04478305", "title": "Affect of Duavive on Mood & Anxiety Symptoms", "sponsor": "St. Joseph's Healthcare Hamilton", "sponsor_class": "OTHER", "phase": "Phase 1", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-07-03", "primary_completion": "2025-12 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "Canada" ], "sex": "Female", "last_update": "2024-12-03", "first_posted": "2020-07-20", "results_posted": "", "conditions": "Menopause; Depression, Anxiety; Sleep; Menopause Related Conditions", "flags": [], "phase_group": "Phase 1" }, { "registry": "ClinicalTrials.gov", "id": "NCT06710015", "url": "https://clinicaltrials.gov/study/NCT06710015", "title": "Study on Fertility Parameters in Women With Germline Variants in BRCA1 and BRCA2", "sponsor": "Fondazione Policlinico Universitario Agostino Gemelli IRCCS", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2024-12-01 (est.)", "primary_completion": "2025-12-01 (est.)", "enrollment": 128, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2024-11-29", "first_posted": "2024-11-29", "results_posted": "", "conditions": "BRCA1 and/or BRCA2 Variant Carriers; Fertility; Reproductive Age; Menopause; Pregnancy Outcomes", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06709664", "url": "https://clinicaltrials.gov/study/NCT06709664", "title": "Perimenopause and Menopause in Women With Spinal Cord Injury", "sponsor": "James Cooper", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-01 (est.)", "primary_completion": "2025-08 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2024-11-29", "first_posted": "2024-11-29", "results_posted": "", "conditions": "Menopause; Spinal Cord Injury", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06611514", "url": "https://clinicaltrials.gov/study/NCT06611514", "title": "Effect of Intravaginal Prasterone on Symptoms of Genitourinary Syndrome of Menopause (GSM) in Women in Menopause With Previous Breast Cancer", "sponsor": "European Institute of Oncology", "sponsor_class": "OTHER", "phase": "Phase 3", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2024-12-01 (est.)", "primary_completion": "2027-01-01 (est.)", "enrollment": 95, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2024-11-19", "first_posted": "2024-09-25", "results_posted": "", "conditions": "Women With Breast Cancer", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06082817", "url": "https://clinicaltrials.gov/study/NCT06082817", "title": "An Open-Label Study of 50 Mg Oral Testosterone Undecanoate (Kyztrex) in Menopausal Women with Low Testosterone and HSDD", "sponsor": "San Diego Sexual Medicine", "sponsor_class": "OTHER", "phase": "Phase 2", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-01-01 (est.)", "primary_completion": "2025-12-31 (est.)", "enrollment": 30, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2024-11-13", "first_posted": "2023-10-13", "results_posted": "", "conditions": "Hypoactive Sexual Desire Disorder", "flags": [], "phase_group": "Phase 2" }, { "registry": "ClinicalTrials.gov", "id": "NCT06659380", "url": "https://clinicaltrials.gov/study/NCT06659380", "title": "Probiotic Efficacy in Postmenopausal Women with Bacterial Vaginosis", "sponsor": "Hasanuddin University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-06-26", "primary_completion": "2024-12-31 (est.)", "enrollment": 12, "enrollment_type": "Estimated", "countries": [ "Indonesia" ], "sex": "Female", "last_update": "2024-10-28", "first_posted": "2024-10-26", "results_posted": "", "conditions": "Bacterial Vaginosis (BV); Menopause", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06634550", "url": "https://clinicaltrials.gov/study/NCT06634550", "title": "Effect of Mulligan Technique Versus Core Stability Exercises on Low Back Pain in Post Menopausal Women", "sponsor": "Cairo University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2024-10-15 (est.)", "primary_completion": "2025-01-15 (est.)", "enrollment": 60, "enrollment_type": "Estimated", "countries": [ "Egypt" ], "sex": "Female", "last_update": "2024-10-10", "first_posted": "2024-10-10", "results_posted": "", "conditions": "Low Back Pain", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06578715", "url": "https://clinicaltrials.gov/study/NCT06578715", "title": "Emotional Freedom Technique (EFT) Applied to Postmenopausal Women on Sleep and Quality of Life", "sponsor": "Ataturk University", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2024-10-01 (est.)", "primary_completion": "2024-10-01 (est.)", "enrollment": 80, "enrollment_type": "Estimated", "countries": [], "sex": "Female", "last_update": "2024-10-02", "first_posted": "2024-08-29", "results_posted": "", "conditions": "Menopause Related Conditions", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06336564", "url": "https://clinicaltrials.gov/study/NCT06336564", "title": "Microablative Radiofrequency in the Treatment of Urinary Symptoms Associated With Genitourinary Syndrome of Menopause", "sponsor": "Centro de Aten\u00e7\u00e3o ao Assoalho P\u00e9lvico", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2025-08 (est.)", "primary_completion": "2026-08 (est.)", "enrollment": 40, "enrollment_type": "Estimated", "countries": [ "Brazil" ], "sex": "Female", "last_update": "2024-08-20", "first_posted": "2024-03-28", "results_posted": "", "conditions": "Menopause; Urinary Incontinence", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT06530459", "url": "https://clinicaltrials.gov/study/NCT06530459", "title": "The MUSE Study for Menopausal Arthralgia", "sponsor": "National University Hospital, Singapore", "sponsor_class": "OTHER", "phase": "Phase 2, Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-08-01 (est.)", "primary_completion": "2027-04 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Singapore" ], "sex": "Female", "last_update": "2024-07-31", "first_posted": "2024-07-31", "results_posted": "", "conditions": "Arthralgia; Menopause; Perimenopausal Disorder; Joint Pain; Postmenopausal Disorder", "flags": [], "phase_group": "Phase 2/3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06487130", "url": "https://clinicaltrials.gov/study/NCT06487130", "title": "Virtual perI-/Menopause Registry of AusTrALia", "sponsor": "Bespoke Clinical Research", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-08-03", "primary_completion": "2073-08 (est.)", "enrollment": 10000, "enrollment_type": "Estimated", "countries": [ "Australia" ], "sex": "All", "last_update": "2024-07-05", "first_posted": "2024-07-05", "results_posted": "", "conditions": "Menopause; Perimenopausal Disorder; Postmenopausal Symptoms; Health Knowledge, Attitudes, Practice; Healthy Aging; Health Care Utilization; Health Care Seeking Behavior; Mental Health Impairment; Mental Deterioration; Mental Health Issue; Osteoporosis, Postmenopausal; Diabetes Mellitus Risk; Diabetes Mellitus, Type 2; Dementia; Cardiovascular Diseases; Menopause Related Conditions; Hot Flashes; Hot Flushes Aggravated; Economic Burden; Social Stigma", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT04196595", "url": "https://clinicaltrials.gov/study/NCT04196595", "title": "Apple Women's Health Study", "sponsor": "Apple Inc.", "sponsor_class": "INDUSTRY", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2019-11-14", "primary_completion": "2029-11 (est.)", "enrollment": 500000, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "All", "last_update": "2024-07-03", "first_posted": "2019-12-12", "results_posted": "", "conditions": "Menstrual Cycle; Ovulation; Menstruation; Polycystic Ovary Syndrome; Infertility; Menopause; Reproduction; Reproductive Health", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06264882", "url": "https://clinicaltrials.gov/study/NCT06264882", "title": "Cardiometabolic Consequences of the Loss of Ovarian Function", "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-06-01", "primary_completion": "2028-05-31 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2024-06-20", "first_posted": "2024-02-20", "results_posted": "", "conditions": "Menopause; Estrogen Deficiency; Aging; Adiposity", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT05280028", "url": "https://clinicaltrials.gov/study/NCT05280028", "title": "HRT on Overactive Bladder Symptoms, Sexual Function, Depressive Symptoms, Autonomic Function, and Arterial Stiffness", "sponsor": "Far Eastern Memorial Hospital", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2022-02-07", "primary_completion": "2026-12-31 (est.)", "enrollment": 100, "enrollment_type": "Estimated", "countries": [ "Taiwan" ], "sex": "Female", "last_update": "2024-06-17", "first_posted": "2022-03-15", "results_posted": "", "conditions": "Menopausal Syndrome", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT05586724", "url": "https://clinicaltrials.gov/study/NCT05586724", "title": "Micronized Progesterone Versus Norethisterone Acetate in Combination With Estrogen as Menopausal Hormone Therapy", "sponsor": "Angelica Lind\u00e9n Hirschberg", "sponsor_class": "OTHER", "phase": "Phase 3", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2022-03-15", "primary_completion": "2026-09 (est.)", "enrollment": 520, "enrollment_type": "Estimated", "countries": [ "Sweden" ], "sex": "Female", "last_update": "2024-06-04", "first_posted": "2022-10-19", "results_posted": "", "conditions": "Menopausal Symptoms", "flags": [], "phase_group": "Phase 3" }, { "registry": "ClinicalTrials.gov", "id": "NCT06151028", "url": "https://clinicaltrials.gov/study/NCT06151028", "title": "An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy", "sponsor": "Anhui Provincial Hospital", "sponsor_class": "OTHER_GOV", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2023-12-01", "primary_completion": "2028-12-31 (est.)", "enrollment": 490, "enrollment_type": "Estimated", "countries": [ "China" ], "sex": "Female", "last_update": "2024-03-07", "first_posted": "2023-11-30", "results_posted": "", "conditions": "Gynecological Malignancies; Menopausal Symptoms; Bone Loss", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT06261658", "url": "https://clinicaltrials.gov/study/NCT06261658", "title": "Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma", "sponsor": "IRCCS Azienda Ospedaliero-Universitaria di Bologna", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2024-03-01 (est.)", "primary_completion": "2024-12-29 (est.)", "enrollment": 45, "enrollment_type": "Estimated", "countries": [ "Italy" ], "sex": "Female", "last_update": "2024-02-15", "first_posted": "2024-02-15", "results_posted": "", "conditions": "Cryopreservation; Ovary Injury; Infertility, Female; Menopause Ovarian Failure", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT04043520", "url": "https://clinicaltrials.gov/study/NCT04043520", "title": "Bioenergetic Effects of Aging and Menopause (BEAM)", "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "phase": "Phase 4", "study_type": "Interventional", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2019-09-24", "primary_completion": "2024-08-31 (est.)", "enrollment": 57, "enrollment_type": "Estimated", "countries": [ "United States" ], "sex": "Female", "last_update": "2023-12-18", "first_posted": "2019-08-02", "results_posted": "", "conditions": "Menopause; Obesity, Abdominal; Aging; Weight Gain", "flags": [], "phase_group": "Phase 4" }, { "registry": "ClinicalTrials.gov", "id": "NCT05985447", "url": "https://clinicaltrials.gov/study/NCT05985447", "title": "Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity", "sponsor": "Heinrich-Heine University, Duesseldorf", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2022-03-07", "primary_completion": "2025-12 (est.)", "enrollment": 180, "enrollment_type": "Estimated", "countries": [ "Germany" ], "sex": "All", "last_update": "2023-08-14", "first_posted": "2023-08-14", "results_posted": "", "conditions": "Arteriosclerosis; Acute Myocardial Infarction; Cardiovascular Events; Menopause", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT05647876", "url": "https://clinicaltrials.gov/study/NCT05647876", "title": "A Longitudinal Study to Identify Mechanisms of Menopause on Cardiovascular Disease Risk", "sponsor": "University of Copenhagen", "sponsor_class": "OTHER", "phase": "Observational", "study_type": "Observational", "status_code": "RECRUITING", "status": "Recruiting", "open": true, "start": "2022-12-16", "primary_completion": "2040-12 (est.)", "enrollment": 200, "enrollment_type": "Estimated", "countries": [ "Denmark" ], "sex": "Female", "last_update": "2023-05-10", "first_posted": "2022-12-13", "results_posted": "", "conditions": "Menopause; Cardiovascular Diseases; Vascular Dilation; Physical Activity", "flags": [], "phase_group": "Observational" }, { "registry": "ClinicalTrials.gov", "id": "NCT05613504", "url": "https://clinicaltrials.gov/study/NCT05613504", "title": "Study of Acupuncture in the Treatment of Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.", "sponsor": "Nanjing University of Traditional Chinese Medicine", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2022-12-01 (est.)", "primary_completion": "2027-12-01 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "China" ], "sex": "Female", "last_update": "2022-11-16", "first_posted": "2022-11-14", "results_posted": "", "conditions": "Hot Flashes; Breast Cancer; Acupuncture", "flags": [], "phase_group": "N/A (non-drug)" }, { "registry": "ClinicalTrials.gov", "id": "NCT05460819", "url": "https://clinicaltrials.gov/study/NCT05460819", "title": "Acupuncture for Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.", "sponsor": "Nanjing University of Traditional Chinese Medicine", "sponsor_class": "OTHER", "phase": "N/A (non-drug)", "study_type": "Interventional", "status_code": "NOT_YET_RECRUITING", "status": "Not yet recruiting", "open": true, "start": "2022-08-01 (est.)", "primary_completion": "2027-07-31 (est.)", "enrollment": 90, "enrollment_type": "Estimated", "countries": [ "China" ], "sex": "Female", "last_update": "2022-07-20", "first_posted": "2022-07-15", "results_posted": "", "conditions": "Hot Flashes; Breast Cancer; Acupuncture", "flags": [], "phase_group": "N/A (non-drug)" } ] }