Women's-health trial intelligence · PCOS
PCOS clinical trials: what changed
PCOS (polycystic ovary syndrome) trials that are recruiting, newly registered, recently updated or newly reporting results, drawn from both the US registry (ClinicalTrials.gov) and the EU registry (CTIS) on one page. Built for femtech business-development teams, women's-health investors, CROs and advocacy groups.
Also tracking: Endometriosis trials · Menopause trials
185trials on this page (open or active in last 90 days)
144open to recruitment now, or about to open
30registry records updated in last 30 days
73updated in last 90 days
38newly registered in last 90 days
0first results posted in last 90 days (US registry)
The last 90 days at a glance
Counts cover the 185 trials listed below. Site-location figures use the 127 open trials that list at least one site country.
By phase
By status
Most active lead sponsors
Industry-sponsored share (US registry rows): 4%
Where open trials have sites
US: 25 · EU-27: 33 · neither: 70 (of 127; a trial can count in both)
Ireland: PCOS trials with an Irish site
0No open PCOS trials currently list an Irish site. Across all 1,127 PCOS records in both registries, 8 have ever listed a site in Ireland. For Irish advocacy groups that is a visible gap, and for sponsors choosing EU sites it is an untapped country.
Want every trial with an Irish site, across all therapy areas? See the Ireland Trials Monitor preview.
Trial table
Newest registry update first. Every ID links to the official registry record. Download the data: CSV · JSON.
| ID | Title | Lead sponsor | Phase | Status | Start | Primary completion | Enrolment | Site countries | Sex eligible | Last update |
|---|---|---|---|---|---|---|---|---|---|---|
| NCT06143527 ClinicalTrials.gov |
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for PCOS Updated ≤30d | The Foundation for Orthopaedics and Regenerative Medicine | Phase 1 | Recruiting | 2023-11-16 | 2027-11-16 (est.) | 20 | Greece, United States | Female | 2026-10-20 |
| 2025-523358-15-00 EU CTIS |
CoCo-PCOS - Comprehensive Health Effects of Combined Contraceptives: a 6-month randomized, controlled, open-label trial of E4+DRSP, EE20µg+DRSP, and DRSP-only in women with PCOS Updated ≤30d | Pohjois-Pohjanmaan hyvinvointialue, University Of Oulu | Phase 4 | Authorised, recruitment pending | — | — | — | Finland | Female | 2026-10-20 |
| NCT07880366 ClinicalTrials.gov |
The Effect of Lifestyle Program Women With PCOS NewUpdated ≤30d | Government College University Faisalabad | N/A (non-drug) | Active, not recruiting | 2026-06-01 | 2026-09-30 | 30 | Pakistan | Female | 2026-10-19 |
| NCT07298603 ClinicalTrials.gov |
Nutrition Intervention for Women With Polycystic Ovary Syndrome Updated ≤30d | Ondokuz Mayıs University | N/A (non-drug) | Enrolling by invitation | 2025-12-03 | 2027-11-30 (est.) | 36 | Turkey (Türkiye) | Female | 2026-10-16 |
| NCT06204965 ClinicalTrials.gov |
Time-Restricted Eating as a Dietary Intervention for Polyendocrine Metabolic Ovarian Syndrome (PMOS): Protocol for a Randomized Controlled Trial Updated ≤30d | Joanna Bajerska | N/A (non-drug) | Not yet recruiting | 2027-01-09 (est.) | 2027-12-31 (est.) | 84 | Poland | Female | 2026-10-16 |
| NCT07770711 ClinicalTrials.gov |
Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS NewUpdated ≤30d | Dicle University | N/A (non-drug) | Recruiting | 2026-08-13 | 2027-09 (est.) | 90 | Turkey (Türkiye) | Female | 2026-10-16 |
| NCT07874646 ClinicalTrials.gov |
Efficacy of Metformin With and Without Probiotics in Women With PCOS NewUpdated ≤30d | Dhivyaprasath Palaniappan | N/A (non-drug) | Completed | 2024-03-27 | 2024-08-30 | 60 | India | Female | 2026-10-15 |
| NCT07875400 ClinicalTrials.gov |
High Intensity Interval Training Versus Mat Pilates in Women With PCOS NewUpdated ≤30d | Riphah International University | N/A (non-drug) | Not yet recruiting | 2026-10-20 (est.) | 2027-06-30 (est.) | 60 | Pakistan | Female | 2026-10-15 |
| NCT05601336 ClinicalTrials.gov |
Dapagliflozin Versus Metformin and Their Combination in Polycystic Ovary Syndrome Updated ≤30d | Beni-Suef University | Phase 3 | Completed | 2025-05-15 | 2026-05-01 | 200 | Egypt | Female | 2026-10-15 |
| NCT07873294 ClinicalTrials.gov |
Letrozole Versus Letrozole and Inositol NewUpdated ≤30d | Al-Azhar University | N/A (non-drug) | Completed | 2025-08-01 | 2026-08-01 | 100 | Egypt | Female | 2026-10-14 |
| NCT07871149 ClinicalTrials.gov |
PMOS in OSA Pilot Study NewUpdated ≤30d | University of Chicago | N/A (non-drug) | Recruiting | 2026-10 (est.) | 2027-10 (est.) | 10 | United States | Female | 2026-10-13 |
| NCT07871175 ClinicalTrials.gov |
Inspiratory Muscle Training for the Management of Polyendocrine Metabolic Ovarian Syndrome NewUpdated ≤30d | British University In Egypt | N/A (non-drug) | Active, not recruiting | 2026-10-07 | 2026-12-02 (est.) | 40 | Egypt | Female | 2026-10-13 |
| NCT07871851 ClinicalTrials.gov |
Investigation of the Effectiveness of Spinal Stabilization Exercises Added to Aerobic Exercise in Women With Polycystic Ovary Syndrome NewUpdated ≤30d | Inonu University | N/A (non-drug) | Not yet recruiting | 2026-10-01 (est.) | 2026-12-20 (est.) | 20 | — | Female | 2026-10-13 |
| NCT07872501 ClinicalTrials.gov |
Clomiphene Citrate Alone Versus Clomiphene Plus Metformin as First Line Approach for the Treatment of Anovulation in Infertile Patients With Polycystic Ovary Syndrome NewUpdated ≤30d | Independent University Hospital, Pakistan | N/A (non-drug) | Completed | 2025-01-01 | 2025-06-30 | 218 | Pakistan | Female | 2026-10-13 |
| NCT07869017 ClinicalTrials.gov |
Longitudinal Metabolic Assessment in PCOS NewUpdated ≤30d | Karadeniz Technical University | N/A (non-drug) | Completed | 2026-01-18 | 2026-09-15 | 45 | Turkey (Türkiye) | Female | 2026-10-09 |
| NCT06800170 ClinicalTrials.gov |
Treatment of Menstrual Cycle Alterations in Adolescents Updated ≤30d | Lo.Li.Pharma s.r.l | N/A (non-drug) | Completed | 2025-06-01 | 2026-02-02 | 41 | Georgia, Russia | Female | 2026-10-09 |
| NCT07571915 ClinicalTrials.gov |
Health-Related Quality of Life and Metabolic Outcomes in PCOS Updated ≤30d | The Cleveland Clinic | N/A (non-drug) | Active, not recruiting | 2026-06-01 | 2027-05-01 (est.) | 40 | United States | Female | 2026-10-08 |
| NCT05680805 ClinicalTrials.gov |
Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS Updated ≤30d | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 4 | Active, not recruiting | 2023-05-27 | 2026-12-30 (est.) | 150 | Bangladesh | Female | 2026-10-07 |
| NCT06896981 ClinicalTrials.gov |
Semaglutide in Women With Polycystic Ovary Syndrome and Obesity Updated ≤30d | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 2/3 | Completed | 2025-01-01 | 2025-10-31 | 31 | Bangladesh | Female | 2026-10-07 |
| NCT07392476 ClinicalTrials.gov |
Continuous Glucose Monitoring in Polycystic Ovarian Syndrome Updated ≤30d | The Cleveland Clinic | Observational | Recruiting | 2025-12-24 | 2026-12-31 (est.) | 40 | United States | All | 2026-10-06 |
| NCT07589075 ClinicalTrials.gov |
Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation in Women With Polycystic Ovarian Syndrome Updated ≤30d | Beni-Suef University | Phase 4 | Completed | 2023-10-20 | 2024-07-01 | 500 | Egypt | Female | 2026-10-06 |
| NCT02506946 ClinicalTrials.gov |
NAFLD in Adolescents and Young Adults With PCOS Updated ≤30d | Columbia University | Observational | Suspended | 2013-07 | 2027-06 (est.) | 80 | United States | Female | 2026-09-30 |
| NCT07849166 ClinicalTrials.gov |
BRCC36 and Telomerase Levels in Women With Polycystic Ovary Syndrome NewUpdated ≤30d | Cumhuriyet University | Observational | Completed | 2024-02-20 | 2025-02-20 | 60 | Turkey (Türkiye) | Female | 2026-09-30 |
| NCT07585396 ClinicalTrials.gov |
Inositol in Letrozol Resistant PCOS Women Updated ≤30d | Kafrelsheikh University | Phase 2/3 | Completed | 2024-04-10 | 2026-06-10 | 136 | Egypt | Female | 2026-09-29 |
| NCT04257500 ClinicalTrials.gov |
Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS Updated ≤30d | Andrea Roe, MD, MPH | Phase 4 | Completed | 2020-09-03 | 2025-08-22 | 22 | United States | Female | 2026-09-28 |
| NCT07844785 ClinicalTrials.gov |
Metabolic and Hormonal Parameters in Women With Polyendocrine Metabolic Ovarian Syndrome NewUpdated ≤30d | Istinye University | Observational | Not yet recruiting | 2026-09-01 (est.) | 2027-02-01 (est.) | 80 | — | Female | 2026-09-28 |
| NCT06891690 ClinicalTrials.gov |
Use of tDCS Stimulation in Neurological and Gynaecological Conditions Updated ≤30d | Poznan University of Physical Education | N/A (non-drug) | Recruiting | 2025-02-05 | 2026-09-30 (est.) | 300 | Poland | All | 2026-09-24 |
| NCT07746635 ClinicalTrials.gov |
Fecal Microbiota Transplantation for Obese Women With Polyendocrine Metabolic Ovarian Syndrome NewUpdated ≤30d | Shanghai Changzheng Hospital | N/A (non-drug) | Recruiting | 2025-04-15 | 2028-12-31 (est.) | 201 | China | Female | 2026-09-22 |
| NCT06519656 ClinicalTrials.gov |
Efficacy of Mazdutide for Treating PCOS Updated ≤30d | Shanghai Zhongshan Hospital | Phase 1/2 | Completed | 2024-10-21 | 2026-09-01 | 43 | China | Female | 2026-09-21 |
| NCT07811011 ClinicalTrials.gov |
Efficacy of Vildagliptin Versus Metformin in Patients With Polycystic Ovary Syndrome NewUpdated ≤30d | Tanta University | Phase 2/3 | Not yet recruiting | 2026-09-20 (est.) | 2027-03-20 (est.) | 70 | — | Female | 2026-09-21 |
| NCT07169136 ClinicalTrials.gov |
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS) Updated ≤90d | Nemours Children's Clinic | Observational | Recruiting | 2025-09-11 | 2026-12 (est.) | 20 | United States | Female | 2026-09-18 |
| NCT06418347 ClinicalTrials.gov |
Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females Updated ≤90d | Ain Shams University | Phase 3 | Completed | 2024-04-01 | 2025-08-01 | 150 | Egypt | Female | 2026-09-16 |
| NCT03841981 ClinicalTrials.gov |
Body Fat as Determinant of Female Gonadal Dysfunction Updated ≤90d | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | Observational | Completed | 2020-01-31 | 2025-06-30 | 50 | Spain | Female | 2026-09-16 |
| 2024-515982-32-00 EU CTIS |
A Clinical Trial of Tirzepatide (LY3298176) in Subjects With Overweight or Obesity and PCOS-related Ovarian Dysfunction (PERIODS) Updated ≤90d | Rheinische Friedrich-Wilhelms-Universitaet Bonn | Phase 4 | Ongoing, recruiting | 2025-12-09 | — | — | Germany | Female | 2026-09-16 |
| NCT07821073 ClinicalTrials.gov |
Myo-Inositol and Folic Acid for Improving Inflammation in Polycystic Ovary Syndrome NewUpdated ≤90d | Khyber Medical University Peshawar | N/A (non-drug) | Active, not recruiting | 2025-10-11 | 2026-04-15 | 50 | Pakistan | Female | 2026-09-15 |
| NCT07780214 ClinicalTrials.gov |
EHBM-Based Intervention for Polycystic Ovarain Syndrome Among High Female School Students NewUpdated ≤90d | Salwan Abed Laftah | N/A (non-drug) | Not yet recruiting | 2026-10-01 (est.) | 2027-03-10 (est.) | 144 | Iraq | Female | 2026-09-11 |
| NCT07811856 ClinicalTrials.gov |
Effects of Metformin and Theory-Based Education in Women With Polycystic Ovary Syndrome NewUpdated ≤90d | Jerash Private University | Phase 4 | Completed | 2026-08-01 | 2026-08-01 | 900 | Jordan | Female | 2026-09-10 |
| NCT03049462 ClinicalTrials.gov |
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists Updated ≤90d | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 1 | Completed | 2017-03-13 | 2026-08-26 | 55 | United States | All | 2026-09-09 |
| NCT07810998 ClinicalTrials.gov |
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome NewUpdated ≤90d | Tanta University | Phase 2/3 | Not yet recruiting | 2026-09-10 (est.) | 2027-04-30 (est.) | 60 | — | Female | 2026-09-09 |
| NCT07371364 ClinicalTrials.gov |
Mobile Application for Women With Polycystic Ovary Syndrome Updated ≤90d | Istanbul Medipol University Hospital | N/A (non-drug) | Completed | 2026-01-15 | 2026-03-01 | 86 | Turkey (Türkiye) | Female | 2026-09-09 |
| NCT07809503 ClinicalTrials.gov |
Multimodal Ocular Diagnosis-Guided Precision Acupuncture and Lifestyle Intervention for PCOS NewUpdated ≤90d | Peking University Third Hospital | N/A (non-drug) | Recruiting | 2026-07-10 | 2028-12-31 (est.) | 210 | China | Female | 2026-09-09 |
| NCT06206746 ClinicalTrials.gov |
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System Updated ≤90d | May Health | N/A (non-drug) | Terminated | 2024-03-25 | 2026-08-12 | 93 | United States | Female | 2026-09-08 |
| NCT07806656 ClinicalTrials.gov |
Acupuncture for Insulin Resistance in Women With Polycystic Ovary Syndrome NewUpdated ≤90d | Peking University Third Hospital | N/A (non-drug) | Not yet recruiting | 2026-08-20 (est.) | 2029-12-01 (est.) | 204 | China | Female | 2026-09-08 |
| 2024-519354-36-00 EU CTIS |
Continuing ovulation induction with letrozole versus switching to gonadotropins in women with polycystic ovary syndrome (MOVIN-II study) Updated ≤90d | Amsterdam UMC Stichting | Phase 4 | Ongoing, recruiting | 2025-08-01 | — | — | Netherlands | Female | 2026-09-04 |
| NCT07490964 ClinicalTrials.gov |
Polycystic Ovary Syndrome in Type 1 Diabetes Updated ≤90d | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | Observational | Recruiting | 2026-04-01 | 2028-06-30 (est.) | 60 | Spain | All | 2026-09-03 |
| NCT05972928 ClinicalTrials.gov |
Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients Updated ≤90d | Beni-Suef University | Phase 2/3 | Completed | 2024-08-07 | 2025-04-30 | 80 | Egypt | Female | 2026-09-01 |
| NCT05819853 ClinicalTrials.gov |
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome Updated ≤90d | University of Colorado, Denver | Phase 3 | Recruiting | 2023-11-03 | 2028-02-01 (est.) | 80 | United States | Female | 2026-08-31 |
| NCT07793838 ClinicalTrials.gov |
Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS NewUpdated ≤90d | Jerash Private University | Phase 4 | Completed | 2025-08-01 | 2026-02-01 | 400 | Jordan | Female | 2026-08-31 |
| NCT05452642 ClinicalTrials.gov |
The Supporting Understanding of PCOS Education and Research (SUPER) Study Updated ≤90d | University of Michigan | N/A (non-drug) | Completed | 2022-08-15 | 2026-06-13 | 223 | United States | Female | 2026-08-26 |
| NCT05965908 ClinicalTrials.gov |
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome Updated ≤90d | Beni-Suef University | Phase 3 | Completed | 2024-08-01 | 2025-11-30 | 183 | Egypt | Female | 2026-08-25 |
| NCT07718217 ClinicalTrials.gov |
Mindfulness-Based Education For Women With Polycystic Ovary Syndrome Updated ≤90d | Aydin Adnan Menderes University | N/A (non-drug) | Recruiting | 2026-07-20 | 2026-09 (est.) | 78 | Turkey (Türkiye) | Female | 2026-08-21 |
| NCT07780188 ClinicalTrials.gov |
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) NewUpdated ≤90d | Texas A&M University | N/A (non-drug) | Recruiting | 2026-09-01 (est.) | 2028-04-30 (est.) | 36 | United States | Female | 2026-08-21 |
| NCT07727512 ClinicalTrials.gov |
PCOS and Brain Health NewUpdated ≤90d | University of Wisconsin, Madison | Observational | Recruiting | 2026-08-07 | 2028-08 (est.) | 45 | United States | Female | 2026-08-21 |
| NCT07779850 ClinicalTrials.gov |
Myo-Inositol for Ovarian Stimulation and ICSI Outcomes in Women With PCOS NewUpdated ≤90d | Kafrelsheikh University | N/A (non-drug) | Completed | 2024-05-15 | 2025-02-15 | 88 | Egypt | Female | 2026-08-21 |
| NCT07777640 ClinicalTrials.gov |
Intra-Ovarian PRP Compared With Gonadotropin for Ovarian Response in Letrozole-Resistant PCOS NewUpdated ≤90d | Bangladesh Medical University | N/A (non-drug) | Completed | 2025-06-01 | 2026-05-20 | 50 | Bangladesh | Female | 2026-08-20 |
| NCT04355572 ClinicalTrials.gov |
Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS) Updated ≤90d | Yale University | N/A (non-drug) | Recruiting | 2026-09 (est.) | 2028-08-31 (est.) | 60 | United States | Female | 2026-08-20 |
| NCT06339567 ClinicalTrials.gov |
Evaluation of the Venous Thrombotic Biological Profile of Different PCOS Phenotypes: French Cross-sectional Study Updated ≤90d | Fondation Hôpital Saint-Joseph | N/A (non-drug) | Active, not recruiting | 2024-02-08 | 2026-01-07 | 352 | France | Female | 2026-08-18 |
| NCT07769476 ClinicalTrials.gov |
Comparison of Clomiphene Alone Versus Clomiphene Plus Sildenafil for Ovulation in Women With Polycystic Ovary Syndrome NewUpdated ≤90d | Nishtar Medical University | Phase 4 | Completed | 2025-07-01 | 2025-12-30 | 98 | Pakistan | Female | 2026-08-18 |
| NCT07766590 ClinicalTrials.gov |
Magnesium Oxide and Letrozole Versus Letrozole Alone on Ovarian Response in Insulin Resistant PCOS NewUpdated ≤90d | Bangladesh Medical University | N/A (non-drug) | Completed | 2025-06-01 | 2026-05-15 | 60 | Bangladesh | Female | 2026-08-14 |
| NCT07764328 ClinicalTrials.gov |
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms. NewUpdated ≤90d | Mila Mend Inc. | N/A (non-drug) | Recruiting | 2025-12-23 | 2026-10-27 (est.) | 225 | United States | Female | 2026-08-13 |
| NCT07759518 ClinicalTrials.gov |
Letrozole High Dose (10 mg) Compared to Letrozole Low Dose( 5 mg) for Ovarian Stimulation in Infertile Women With Polycystic Ovary Syndrome NewUpdated ≤90d | Mst.Sumyara Khatun | N/A (non-drug) | Completed | 2025-02-01 | 2026-02-01 | 86 | Bangladesh | Female | 2026-08-12 |
| NCT07759674 ClinicalTrials.gov |
Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan NewUpdated ≤90d | Jerash Private University | Phase 4 | Completed | 2023-06-01 | 2023-09-01 | 25 | Jordan | Female | 2026-08-12 |
| NCT07412028 ClinicalTrials.gov |
Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS) Updated ≤90d | Assistance Publique - Hôpitaux de Paris | N/A (non-drug) | Recruiting | 2026-07-21 | 2028-01 (est.) | 81 | France | Female | 2026-08-10 |
| NCT07750899 ClinicalTrials.gov |
The Effect of Standardized Withania Somnifera Extract on Endocrine, Metabolic, and Psychometric Parameters, in Women With Polyendocrine Metabolic Ovarian Syndrome NewUpdated ≤90d | Medical University of Lodz | N/A (non-drug) | Completed | 2025-01-16 | 2025-11-20 | 28 | Poland | Female | 2026-08-06 |
| NCT07394530 ClinicalTrials.gov |
Comparison of IVF Outcomes Between PPOS and Antagonist Protocols in Women With PCOS Updated ≤90d | Hanoi General Hospital (Vietnam) | N/A (non-drug) | Recruiting | 2026-01-20 | 2027-06-30 (est.) | 400 | Vietnam | Female | 2026-08-05 |
| NCT07747909 ClinicalTrials.gov |
Effect of Orlistat on Metabolic and Hormonal Features in Women With Polycystic Ovary Syndrome (PCOS): a Randomized Controlled Clinical Trial NewUpdated ≤90d | Khyber Medical University Peshawar | N/A (non-drug) | Recruiting | 2026-01-01 | 2026-08-10 (est.) | 120 | Pakistan | Female | 2026-08-05 |
| NCT07739940 ClinicalTrials.gov |
Clinical Research Cohort for Polycystic Ovary Syndrome NewUpdated ≤90d | Guangdong Women and Children Hospital | Observational | Active, not recruiting | 2025-07-28 | 2026-12-01 (est.) | 420 | China | Female | 2026-07-31 |
| NCT07739953 ClinicalTrials.gov |
Development and Clinical Application of ApoC3 Protein as a Predictive Biomarker for Insulin Resistance in Polycystic Ovary Syndrome NewUpdated ≤90d | Guangdong Women and Children Hospital | Observational | Active, not recruiting | 2025-06-01 | 2026-12-31 (est.) | 200 | China | Female | 2026-07-31 |
| NCT07736079 ClinicalTrials.gov |
Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary Syndrome NewUpdated ≤90d | GÜLDEN ANATACA | Observational | Not yet recruiting | 2026-07-30 (est.) | 2026-09-30 (est.) | 60 | — | Female | 2026-07-30 |
| NCT07731373 ClinicalTrials.gov |
Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS) NewUpdated ≤90d | Kayseri City Hospital | Observational | Not yet recruiting | 2026-09-01 (est.) | 2027-04-30 (est.) | 150 | Turkey (Türkiye) | Female | 2026-07-30 |
| NCT07571096 ClinicalTrials.gov |
Construction of a Multi-dimensional Risk Assessment System: a Clinical Study of Polycystic Ovary Syndrome Complicated With Thrombophilia Updated ≤90d | Guangdong Women and Children Hospital | Observational | Recruiting | 2025-03-04 | 2026-08-01 (est.) | 100 | China | Female | 2026-07-30 |
| NCT07727863 ClinicalTrials.gov |
Effect of Estradiol Pretreatment on Follicular Synchronization and IVF Outcomes in Women With Polycystic Ovary Syndrome Undergoing ICSI Using GnRH Antagonist Protocol NewUpdated ≤90d | Cairo University | N/A (non-drug) | Completed | 2024-09-13 | 2026-02-17 | 61 | Egypt | Female | 2026-07-27 |
| NCT07723443 ClinicalTrials.gov |
Effects of Folic Acid and Vitamin E on Hormones in Polycystic Ovary Syndrome NewUpdated ≤90d | Al-Mustansiriyah University | N/A (non-drug) | Completed | 2025-07-01 | 2026-02-10 | 207 | Iraq | Female | 2026-07-23 |
| NCT07708766 ClinicalTrials.gov |
Effect of High Intensity Interval Training on Insulin Resistance in Polycystic Ovarian Syndrome | Cairo University | N/A (non-drug) | Not yet recruiting | 2026-07-20 (est.) | 2027-01-15 (est.) | 50 | Egypt | Female | 2026-07-16 |
| NCT07698925 ClinicalTrials.gov |
Diaphragmatic Breathing Exercises on Sleep Disorders un Polycystic Ovarian Syndrome | Adly A Adam | N/A (non-drug) | Recruiting | 2026-07-11 | 2026-09-01 (est.) | 54 | Egypt | Female | 2026-07-14 |
| NCT07687667 ClinicalTrials.gov |
Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS | Peking University Third Hospital | N/A (non-drug) | Not yet recruiting | 2026-07 (est.) | 2028-12 (est.) | 406 | China | Female | 2026-07-07 |
| NCT07687264 ClinicalTrials.gov |
Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS) | University of Zurich | N/A (non-drug) | Not yet recruiting | 2026-08-01 (est.) | 2029-07-30 (est.) | 40 | Switzerland | Female | 2026-07-07 |
| NCT07659392 ClinicalTrials.gov |
Physical Activity and Cardiometabolic Health in Women With or Without Polycystic Ovary Syndrome (SCOPAP) | University Hospital, Clermont-Ferrand | N/A (non-drug) | Not yet recruiting | 2026-07 (est.) | 2028-12 (est.) | 40 | France | Female | 2026-06-22 |
| NCT07509762 ClinicalTrials.gov |
Exercise Programs in Women With PCOS | Biruni University | N/A (non-drug) | Not yet recruiting | 2026-09-01 (est.) | 2027-01-15 (est.) | 33 | Turkey (Türkiye) | Female | 2026-06-17 |
| NCT07645014 ClinicalTrials.gov |
Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome. | Riphah International University | N/A (non-drug) | Recruiting | 2025-10-01 | 2026-07-01 (est.) | 38 | Pakistan | Female | 2026-06-12 |
| NCT07499518 ClinicalTrials.gov |
Fertility and Polycystic Ovary Syndrome | Assistance Publique - Hôpitaux de Paris | Observational | Not yet recruiting | 2026-06-01 (est.) | 2027-06-01 (est.) | 473 | France | Female | 2026-06-10 |
| NCT07629895 ClinicalTrials.gov |
Myo-Inositol Alone Versus Myo-Inositol Plus Alpha-Lactalbumin in Women With Polycystic Ovary Syndrome | Quaid-e-Azam Medical College | N/A (non-drug) | Not yet recruiting | 2026-09 (est.) | 2027-04 (est.) | 82 | Pakistan | Female | 2026-06-09 |
| NCT07630441 ClinicalTrials.gov |
Theta Healing-Based Intervention in Women With Polycystic Ovary Syndrome | Ankara Medipol University | N/A (non-drug) | Not yet recruiting | 2026-06-08 (est.) | 2026-07-24 (est.) | 142 | Turkey (Türkiye) | Female | 2026-06-05 |
| NCT07630779 ClinicalTrials.gov |
Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients | Beni-Suef University | Phase 3 | Recruiting | 2026-03-10 | 2026-09-10 (est.) | 180 | Egypt | Female | 2026-06-05 |
| NCT07598344 ClinicalTrials.gov |
MeDiApp-PCOS: A Mobile Mediterranean Diet App for Women With Polycystic Ovary Syndrome | Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health | N/A (non-drug) | Not yet recruiting | 2026-05-13 (est.) | 2028-12-30 (est.) | 60 | — | Female | 2026-06-03 |
| NCT07623551 ClinicalTrials.gov |
Observational Study on the Causal Architecture of Polycystic Ovary Syndrome (PCOS) | AnnieGuard Corp. | Observational | Not yet recruiting | 2026-06 (est.) | 2026-07 (est.) | 100 | — | Female | 2026-06-03 |
| NCT06852365 ClinicalTrials.gov |
Combined Oral Contraceptive Pill and Resistance Starch | University of Pennsylvania | Phase 2 | Recruiting | 2025-06-10 | 2028-04 (est.) | 100 | United States | Female | 2026-06-01 |
| NCT05979389 ClinicalTrials.gov |
Bicalutamide Therapy in Young Women With NAFLD and PCOS | University of California, San Francisco | Phase 1 | Recruiting | 2024-02-14 | 2028-08 (est.) | 50 | United States | Female | 2026-05-29 |
| NCT07616037 ClinicalTrials.gov |
Efficacy of a GLP-1/FGF21 Dual Agonist for Treating PCOS | Shanghai Zhongshan Hospital | Phase 2 | Recruiting | 2026-06 (est.) | 2027-06 (est.) | 30 | China | Female | 2026-05-29 |
| NCT07591246 ClinicalTrials.gov |
Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction | Cairo University | N/A (non-drug) | Recruiting | 2026-03-07 | 2026-12-30 (est.) | 40 | Egypt | Female | 2026-05-15 |
| NCT07227363 ClinicalTrials.gov |
Symptoms of Polycystic Ovarian Syndrome Ameliorated by Keto-Adaptation Pilot | Ohio State University | N/A (non-drug) | Recruiting | 2026-12-01 (est.) | 2026-12 (est.) | 40 | United States | Female | 2026-05-08 |
| NCT05950282 ClinicalTrials.gov |
Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis | Ali Chappell | Observational | Recruiting | 2024-02-01 | 2027-10 (est.) | 150 | United States | All | 2026-05-01 |
| NCT03059173 ClinicalTrials.gov |
Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome | University Hospital, Lille | Phase 3 | Recruiting | 2023-09-12 | 2027-09-12 (est.) | 276 | France | Female | 2026-04-22 |
| NCT07533968 ClinicalTrials.gov |
The Aim of This Study is to Gain Insight Into the Occurrence of Irritable Bowel Symptoms During Ovarian Stimulation in Individuals With PCOS and in Women Who Wish to Freeze Their Eggs. This Study Uses Questionnaires. | Universitair Ziekenhuis Brussel | N/A (non-drug) | Not yet recruiting | 2026-04-20 (est.) | 2027-03-01 (est.) | 120 | — | Female | 2026-04-16 |
| NCT06124261 ClinicalTrials.gov |
Androgens and NAFLD Longitudinal Cohort Study | University of California, San Francisco | Observational | Recruiting | 2024-01-22 | 2028-12 (est.) | 150 | United States | Female | 2026-04-13 |
| NCT06887881 ClinicalTrials.gov |
PIMS vs PGT-A in Infertile PCOS Patients | First Affiliated Hospital, Sun Yat-Sen University | N/A (non-drug) | Recruiting | 2025-06-12 | 2028-11 (est.) | 766 | China | Female | 2026-04-02 |
| NCT07102797 ClinicalTrials.gov |
ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence | Massachusetts General Hospital | N/A (non-drug) | Recruiting | 2025-11-24 | 2027-12 (est.) | 40 | United States | Female | 2026-03-19 |
| NCT07483723 ClinicalTrials.gov |
Glucose Profiles in Women With Polycystic Ovary Syndrome | Centre Hospitalier Universitaire, Amiens | N/A (non-drug) | Recruiting | 2026-01-06 | 2027-07 (est.) | 80 | France | Female | 2026-03-19 |
| NCT07465575 ClinicalTrials.gov |
Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) | Liaquat University of Medical & Health Sciences | N/A (non-drug) | Not yet recruiting | 2026-03-16 (est.) | 2027-02-19 (est.) | 150 | Italy | Female | 2026-03-19 |
| NCT06793085 ClinicalTrials.gov |
Pro- and Anti-inflammatory Cytokines in PCOS | Jagiellonian University | Observational | Recruiting | 2025-01-20 | 2026-06-30 (est.) | 100 | Poland | Female | 2026-03-18 |
| NCT06793072 ClinicalTrials.gov |
Adipokines in Polycystic Ovary Syndrome | Jagiellonian University | Observational | Recruiting | 2025-01-20 | 2027-12-31 (est.) | 300 | Poland | Female | 2026-03-18 |
| NCT06793098 ClinicalTrials.gov |
Functional Proteins in Polycystic Ovary Syndrome | Jagiellonian University | Observational | Recruiting | 2025-01-20 | 2027-12-01 (est.) | 100 | Poland | Female | 2026-03-18 |
| NCT06551285 ClinicalTrials.gov |
Study of the Effect of a Nutritional Supplement on Microbiota, Metabolic Control, Inflammatory Profile, and Quality of Life in Patients With Polycystic Ovary Syndrome. | Celia Bañuls | N/A (non-drug) | Recruiting | 2024-02-01 | 2026-12-31 (est.) | 120 | Spain | Female | 2026-03-17 |
| NCT07459595 ClinicalTrials.gov |
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study | Fatima Tariq | Phase 1 | Not yet recruiting | 2026-05-01 (est.) | 2026-07-31 (est.) | 60 | Pakistan | Female | 2026-03-10 |
| NCT06047574 ClinicalTrials.gov |
Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome | Shanghai 10th People's Hospital | Observational | Recruiting | 2023-09-18 | 2026-06-30 (est.) | 3,000 | China | Female | 2026-03-09 |
| NCT07446985 ClinicalTrials.gov |
Is There a Benefit From Addition of Physical Exercise to Diet Restriction/Limitation in PCOS Women With Asthma? | Cairo University | N/A (non-drug) | Recruiting | 2026-02-07 | 2026-06-30 (est.) | 40 | Egypt | Female | 2026-03-03 |
| NCT07426146 ClinicalTrials.gov |
Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan | Shanghai First Maternity and Infant Hospital | Observational | Recruiting | 2025-08-10 | 2026-02-10 (est.) | 56 | China | Female | 2026-02-23 |
| NCT07403201 ClinicalTrials.gov |
The Effect of Therapy Combination in PCOS With Dlbs 3233 | Inlacinpenelitian | Early Phase 1 | Recruiting | 2021-12-15 | 2026-01-31 | 90 | Indonesia | Female | 2026-02-11 |
| NCT07396402 ClinicalTrials.gov |
SCUBE Proteins in Polycystic Ovary Syndrome (IPSOS) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A (non-drug) | Not yet recruiting | 2026-01-15 (est.) | 2026-07-01 (est.) | 56 | Italy | Female | 2026-02-09 |
| NCT05326087 ClinicalTrials.gov |
Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-A | ShangHai Ji Ai Genetics & IVF Institute | Phase 3 | Not yet recruiting | 2026-06-01 (est.) | 2027-12-01 (est.) | 204 | — | Female | 2026-02-02 |
| NCT07366944 ClinicalTrials.gov |
PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes | Cairo University | N/A (non-drug) | Recruiting | 2025-12-05 | 2026-06-05 (est.) | 40 | Egypt | Female | 2026-01-26 |
| NCT07350889 ClinicalTrials.gov |
Effects of a Specific Dietary Program on Overweight/Obese Women With Polycystic Ovary Syndrome: A Multicenter, Prospective, Randomized Controlled Clinical Study | Xuanwu Hospital, Beijing | N/A (non-drug) | Not yet recruiting | 2026-01-15 (est.) | 2027-12-31 (est.) | 160 | China | Female | 2026-01-20 |
| NCT07342946 ClinicalTrials.gov |
The Effects of the Mediterranean Diet and Synbiotics in Polycystic Ovary Syndrome | Atlas University | N/A (non-drug) | Not yet recruiting | 2025-12-20 (est.) | 2027-04-01 (est.) | 32 | — | Female | 2026-01-15 |
| NCT07339930 ClinicalTrials.gov |
Phenotyping of Patients With Polycystic Ovary Syndrome | University Hospital, Strasbourg, France | Observational | Recruiting | 2025-09-17 | 2026-09 (est.) | 100 | France | All | 2026-01-14 |
| NCT07326111 ClinicalTrials.gov |
A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese | University of Bonn | Phase 4 | Recruiting | 2025-12-09 | 2028-12 (est.) | 198 | Germany | Female | 2026-01-08 |
| NCT07322120 ClinicalTrials.gov |
Light Fasting Diet and Magnesium in Polycystic Ovary Syndrome (PCOS) | Behnood Abbasi | N/A (non-drug) | Not yet recruiting | 2026-02-20 (est.) | 2026-05-22 (est.) | 46 | — | Female | 2026-01-07 |
| NCT07307677 ClinicalTrials.gov |
Melatonin & Metformin on Clinical & Biochemical Parameters in Insulin Resistant PCOS Compared to Metformin | Mst.Sumyara Khatun | N/A (non-drug) | Recruiting | 2025-03-11 | 2026-03-10 (est.) | 60 | Bangladesh | Female | 2026-01-07 |
| NCT07298564 ClinicalTrials.gov |
Effect of Magnesium and Levocarnitine on Metabolic and Clinical Outcomes in Women With Polycystic Ovarian Syndrome (PCOS) | Behnood Abbasi | N/A (non-drug) | Recruiting | 2026-01-30 (est.) | 2026-10-30 (est.) | 84 | Iran | Female | 2025-12-23 |
| NCT07266259 ClinicalTrials.gov |
Effect of Levocarnitine Plus Myoinositol Versus Myoinositol Alone on Hormonal and Insulin Resistance in PCOS Women | Mst.Sumyara Khatun | N/A (non-drug) | Recruiting | 2025-09-19 | 2026-08-18 (est.) | 72 | Bangladesh | Female | 2025-12-19 |
| NCT07242131 ClinicalTrials.gov |
Efficacy of Oral Contraceptive, Progesterone, and Inositol on Menstrual Regulation in PCOS | Ege University | N/A (non-drug) | Recruiting | 2025-12-01 | 2026-06-01 (est.) | 150 | Turkey (Türkiye) | Female | 2025-12-18 |
| NCT07289399 ClinicalTrials.gov |
Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS? | Cairo University | N/A (non-drug) | Recruiting | 2025-10-10 | 2026-05-15 (est.) | 40 | Egypt | Female | 2025-12-17 |
| NCT07255911 ClinicalTrials.gov |
Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS | Mst.Sumyara Khatun | N/A (non-drug) | Recruiting | 2025-02-07 | 2026-01-06 (est.) | 72 | Bangladesh | Female | 2025-12-16 |
| NCT06424860 ClinicalTrials.gov |
Fish Oil, Metformin and Heart Health in PCOS | University of Alberta | Phase 1 | Recruiting | 2025-11-01 | 2026-12-30 (est.) | 146 | Canada | Female | 2025-12-12 |
| NCT07274202 ClinicalTrials.gov |
The Physical and Mental Impact of ART: IVM vs Conventional Ovarian Stimulation | Universitair Ziekenhuis Brussel | N/A (non-drug) | Not yet recruiting | 2026-01 (est.) | 2028-01 (est.) | 84 | — | Female | 2025-12-10 |
| NCT06545721 ClinicalTrials.gov |
Weight Cycling on Hyperandrogenemia and Insulin Resistance in Polycystic Ovary Syndrome | Peking Union Medical College Hospital | N/A (non-drug) | Recruiting | 2024-08-13 | 2026-03-01 (est.) | 425 | China | All | 2025-12-03 |
| NCT07159880 ClinicalTrials.gov |
Letrozole Extended vs Traditional Therapy for Ovulation Induction in Women With PCOS (PROLEx-PCOS) | GABRIEL MONTEIRO PINHEIRO | N/A (non-drug) | Recruiting | 2025-09-01 | 2026-07-30 (est.) | 20 | Brazil | Female | 2025-11-28 |
| NCT07197255 ClinicalTrials.gov |
Transcriptomic Profiling of Cumulus Cells From CAPA-IVM | Mỹ Đức Hospital | Observational | Recruiting | 2025-10-16 | 2026-01-30 (est.) | 10 | Vietnam | Female | 2025-11-21 |
| NCT06889454 ClinicalTrials.gov |
Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOS | Attikon Hospital | Observational | Recruiting | 2024-02-01 | 2025-02-01 | 120 | Greece | Female | 2025-11-19 |
| NCT07171970 ClinicalTrials.gov |
IVM - Fresh ET (THE SAIGON PROTOCOL) Versus IVF - FET in PCOS Women | Mỹ Đức Hospital | N/A (non-drug) | Recruiting | 2025-09-22 | 2027-10-01 (est.) | 600 | Vietnam | Female | 2025-10-01 |
| NCT07189247 ClinicalTrials.gov |
Evaluation of Fibromyalgia Frequency and Pain Parameters in Women With Polycystic Ovary Syndrome | Ufuk University | Observational | Not yet recruiting | 2025-11-01 (est.) | 2026-11-01 (est.) | 140 | Turkey (Türkiye) | Female | 2025-09-23 |
| NCT07182526 ClinicalTrials.gov |
Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome | Al-Mustansiriyah University | Phase 2 | Recruiting | 2025-09-20 (est.) | 2026-05-01 (est.) | 150 | Iraq | All | 2025-09-19 |
| NCT07169292 ClinicalTrials.gov |
Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients | Princess Nourah Bint Abdulrahman University | N/A (non-drug) | Not yet recruiting | 2026-01-01 (est.) | 2026-06-30 (est.) | 60 | Saudi Arabia | Female | 2025-09-11 |
| NCT06807775 ClinicalTrials.gov |
Time Restricted Feeding Model in Women With Polycystic Ovary Syndrome | Hacettepe University | N/A (non-drug) | Not yet recruiting | 2025-10-01 (est.) | 2026-03-01 (est.) | 45 | — | Female | 2025-09-10 |
| NCT07158723 ClinicalTrials.gov |
Protein and Polycystic Ovary Syndrome (PCOS) | University of Arkansas, Fayetteville | N/A (non-drug) | Recruiting | 2025-08-01 | 2027-06-30 (est.) | 60 | United States | Female | 2025-09-08 |
| NCT06041204 ClinicalTrials.gov |
Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism | Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy | N/A (non-drug) | Recruiting | 2021-05-06 | 2026-05-30 (est.) | 200 | Egypt | Female | 2025-09-03 |
| NCT07142603 ClinicalTrials.gov |
Appetite Response to Meals With Different Protein Sources in Women With PCOS | University of Arkansas, Fayetteville | N/A (non-drug) | Recruiting | 2025-08-18 | 2026-12-31 (est.) | 30 | United States | Female | 2025-09-02 |
| NCT07139275 ClinicalTrials.gov |
Insulin Sensitivity and Testosterone Response to Aerobic Exercise Versus Added Sugar Elimination in Polycystic Ovary Syndrome Women | Cairo University | N/A (non-drug) | Not yet recruiting | 2025-08-20 (est.) | 2025-12-20 (est.) | 60 | — | Female | 2025-08-24 |
| NCT07129434 ClinicalTrials.gov |
Strengthening Healthy Emotional Co-regulation of Mothers With PCOS and Obesity and Their Infants | Oulu University Hospital | N/A (non-drug) | Recruiting | 2025-04-15 | 2026-07 (est.) | 40 | Finland | Female | 2025-08-19 |
| NCT07120815 ClinicalTrials.gov |
Optimizing Metformin Use in Polycystic Ovary Syndrome | Helsinki University Central Hospital | Phase 3 | Not yet recruiting | 2025-09-01 (est.) | 2027-12-31 (est.) | 184 | Finland | Female | 2025-08-13 |
| NCT07016035 ClinicalTrials.gov |
Translation and Validation of the French mPCOSQ (mPCOSQ-F). | CHU de Reims | Observational | Recruiting | 2025-05-12 | 2027-05-12 (est.) | 350 | France | Female | 2025-08-07 |
| NCT07106996 ClinicalTrials.gov |
Mechanism of Red Yeast Rice Regulating Intestinal Indole Metabolism Pathway to Improve Chronic Inflammation in Polycystic Ovary Syndrome | Sichuan Provincial People's Hospital | Early Phase 1 | Recruiting | 2025-07-28 | 2026-06-01 (est.) | 90 | China | Female | 2025-08-06 |
| NCT04723862 ClinicalTrials.gov |
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism? | University of Virginia | Early Phase 1 | Recruiting | 2021-11-12 | 2025-10-01 (est.) | 32 | United States | Female | 2025-08-05 |
| NCT06115122 ClinicalTrials.gov |
PEPPI Study: Identification of Women at Risk for Placental Dysfunction | Oulu University Hospital | Observational | Recruiting | 2022-02-15 | 2027-12-31 (est.) | 3,000 | Finland | All | 2025-08-05 |
| NCT03068910 ClinicalTrials.gov |
Hyperandrogenemia and Altered Day-night LH Pulse Patterns | University of Virginia | Early Phase 1 | Recruiting | 2016-07-21 | 2025-10-01 (est.) | 32 | United States | Female | 2025-08-05 |
| NCT03401047 ClinicalTrials.gov |
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome | University of Virginia | Early Phase 1 | Recruiting | 2017-11-30 | 2025-10-01 (est.) | 37 | United States | Female | 2025-08-05 |
| NCT06049420 ClinicalTrials.gov |
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients | West Virginia School of Osteopathic Medicine | N/A (non-drug) | Recruiting | 2025-02-01 | 2027-09-01 (est.) | 95 | United States | All | 2025-07-25 |
| NCT06836128 ClinicalTrials.gov |
The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients | Cairo University | Phase 3 | Recruiting | 2025-03-01 | 2026-02-01 (est.) | 102 | Egypt | Female | 2025-07-09 |
| NCT06742710 ClinicalTrials.gov |
Liraglutide Treatment in Obese Infertile PCOS Women | Peking University Third Hospital | Phase 4 | Recruiting | 2025-05-22 | 2029-05-30 (est.) | 890 | China | Female | 2025-05-29 |
| NCT06842524 ClinicalTrials.gov |
Dihydroartemisinin for the Treatment of Polycystic Ovary Syndrome | Shanghai Zhongshan Hospital | Phase 2 | Recruiting | 2025-04-16 | 2026-09-30 (est.) | 150 | China | Female | 2025-04-20 |
| NCT06912594 ClinicalTrials.gov |
App Impact on Quality of Life and Symptoms in PCOS | Endo Health GmbH | N/A (non-drug) | Not yet recruiting | 2025-04-02 (est.) | 2025-09 (est.) | 220 | Germany | Female | 2025-04-06 |
| NCT05858307 ClinicalTrials.gov |
Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements | Chinese University of Hong Kong | Observational | Recruiting | 2022-06-22 | 2026-06-30 (est.) | 300 | Hong Kong | Female | 2025-03-27 |
| NCT06861803 ClinicalTrials.gov |
Laboratory and Ultrasound Findings and Response to Letrozole in PCOS Patients | Al-Azhar University | Observational | Not yet recruiting | 2025-04-01 (est.) | 2025-12-01 (est.) | 138 | Egypt | Female | 2025-03-21 |
| NCT03989778 ClinicalTrials.gov |
Vitamin D and Polycystic Ovarian Syndrome (PCOS) | Aga Khan University | Phase 2 | Recruiting | 2023-02-01 | 2025-06-30 (est.) | 300 | Pakistan | All | 2025-02-19 |
| NCT06832735 ClinicalTrials.gov |
Health-related Quality of Life of Women with Polycystic Ovary Syndrome At Sohag University Hospital | Sohag University | Observational | Not yet recruiting | 2025-03 (est.) | 2025-09-01 (est.) | 352 | Egypt | Female | 2025-02-18 |
| NCT06045351 ClinicalTrials.gov |
Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome | Aga Khan University | Phase 1 | Recruiting | 2024-01-01 | 2026-06-30 (est.) | 142 | Pakistan | Female | 2025-02-18 |
| 2023-509259-15-01 EU CTIS |
Optimizing metformin use in polycystic ovary syndrome - A randomized controlled trial | HUS-yhtymae | Phase 4 | Authorised, recruitment pending | — | — | — | Finland | Female | 2025-02-09 |
| NCT06793904 ClinicalTrials.gov |
Comparative Study Between HOMA1-IR and HOMA2-IR in Prediction of Ovulation Outcome in Women With PCOS | Cairo University | N/A (non-drug) | Recruiting | 2025-02-01 | 2026-01 (est.) | 122 | Egypt | Female | 2025-02-05 |
| NCT06155708 ClinicalTrials.gov |
Exogenous Ketone Supplementation in Females with Polycystic Ovary Syndrome | McGill University | N/A (non-drug) | Recruiting | 2025-01-20 (est.) | 2027-06 (est.) | 60 | Canada | All | 2025-01-22 |
| NCT06775093 ClinicalTrials.gov |
Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity | Peking University Third Hospital | N/A (non-drug) | Not yet recruiting | 2025-03-01 (est.) | 2026-12-31 (est.) | 392 | China | Female | 2025-01-14 |
| NCT06713967 ClinicalTrials.gov |
Comparison of Pregnancy Outcomes in Women with Polycystic Ovarian Syndrome with and Without Glucophage | University of Health Sciences Lahore | N/A (non-drug) | Not yet recruiting | 2025-02-02 (est.) | 2025-05-25 (est.) | 70 | — | Female | 2024-12-06 |
| NCT03911297 ClinicalTrials.gov |
DAISy-PCOS Phenome Study - Dissecting Androgen Excess and Metabolic Dysfunction in Polycystic Ovary Syndrome | Imperial College London | Observational | Recruiting | 2019-08-14 | 2026-12-31 (est.) | 1,000 | United Kingdom | Female | 2024-12-05 |
| NCT06717087 ClinicalTrials.gov |
Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients | RenJi Hospital | N/A (non-drug) | Not yet recruiting | 2024-12-20 (est.) | 2025-08-01 (est.) | 92 | China | Female | 2024-12-04 |
| NCT04836910 ClinicalTrials.gov |
Microbiome and Polycystic Ovaries | Sheba Medical Center | Observational | Not yet recruiting | 2025-09-01 (est.) | 2027-03-30 (est.) | 40 | Israel | Female | 2024-11-14 |
| NCT05936840 ClinicalTrials.gov |
Quantum Menstrual Health Monitoring Study | Quanovate Tech Inc. | Observational | Recruiting | 2024-05-01 | 2025-05-01 (est.) | 150 | Canada | Female | 2024-10-28 |
| NCT06642363 ClinicalTrials.gov |
The Effectiveness of Astaxanthin Supplementation on the Clinical Symptoms and Cardio-metabolic Profile in Women with Polycystic Ovary Syndrome | Isfahan University of Medical Sciences | Phase 1 | Recruiting | 2024-07-22 | 2025-07-22 (est.) | 44 | Iran | Female | 2024-10-17 |
| 2024-514505-64-01 EU CTIS |
Acupuncture or Metformin for Insulin Resistance in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial | Karolinska Institutet | Phase 3/4 | Ongoing, recruiting | 2024-10-18 | — | — | Sweden | Female | 2024-10-17 |
| NCT06642831 ClinicalTrials.gov |
Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study | University Hospital Erlangen | Observational | Recruiting | 2023-01-31 | 2026-12 (est.) | 380 | Germany | Female | 2024-10-15 |
| NCT06633120 ClinicalTrials.gov |
In Vitro Maturation of Human Eggs | Colorado Center for Reproductive Medicine | N/A (non-drug) | Recruiting | 2023-02-03 | 2029-07-31 (est.) | 50 | United States | Female | 2024-10-09 |
| NCT02647827 ClinicalTrials.gov |
Acupuncture or Metformin for Insulin Resistance in Women With PCOS | Karolinska Institutet | Phase 2 | Recruiting | 2015-12 | 2025-06 (est.) | 303 | China, Sweden | Female | 2024-10-09 |
| NCT06587698 ClinicalTrials.gov |
Sitagliptin or BeiDouGen Capsule Improve the Pregnancy Outcome in Patients with PCOS | Peking University Third Hospital | N/A (non-drug) | Recruiting | 2024-08-21 | 2028-07-01 (est.) | 300 | China | Female | 2024-09-19 |
| NCT04196595 ClinicalTrials.gov |
Apple Women's Health Study | Apple Inc. | Observational | Recruiting | 2019-11-14 | 2029-11 (est.) | 500,000 | United States | All | 2024-07-03 |
| NCT04650880 ClinicalTrials.gov |
Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome | The University of Hong Kong | N/A (non-drug) | Recruiting | 2021-01-26 | 2024-12-31 (est.) | 220 | Hong Kong | Female | 2024-05-14 |
| NCT03742011 ClinicalTrials.gov |
Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study | Guangzhou Women and Children's Medical Center | Observational | Recruiting | 2012-02-01 | 2025-12-31 (est.) | 2,000 | China | All | 2024-02-26 |
| NCT06192147 ClinicalTrials.gov |
The Phenotype and Clinical Intervention of High BCAA Type of PCOS | Peking University Third Hospital | N/A (non-drug) | Not yet recruiting | 2024-01-01 (est.) | 2026-01-01 (est.) | 400 | — | Female | 2024-01-05 |
| NCT06167135 ClinicalTrials.gov |
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort | Semmelweis University | Observational | Recruiting | 2021-09-10 | 2033-09-30 (est.) | 150 | Hungary | Female | 2023-12-18 |
| NCT06102629 ClinicalTrials.gov |
Ovary Syndrome for Efficient Diagnosis and Targeted Therapy | Asian Institute of Gastroenterology, India | N/A (non-drug) | Not yet recruiting | 2023-11-05 (est.) | 2026-11-15 (est.) | 200 | India | All | 2023-10-26 |
| NCT05756023 ClinicalTrials.gov |
IVF\ICSI Outcome in Women With Polycystic Ovary Syndrome | Egymedicalpedia | N/A (non-drug) | Recruiting | 2023-06-01 | 2026-12-01 (est.) | 156 | Egypt | Female | 2023-10-19 |
| 2023-503477-38-00 EU CTIS |
Insemination in patients with polycystic ovary syndrome: gestation rates using two stimulation patterns: letrozole vs gonadotropins. | Hospital Universitario La Paz | Phase 3 | Ongoing, recruiting | 2023-12-15 | — | — | Spain | Female | 2023-10-09 |
| NCT02010814 ClinicalTrials.gov |
Characterization of a Prospective Cohort of Women With PCOS | Odense University Hospital | Observational | Recruiting | 2012-01-01 | 2027-01-01 (est.) | 500 | Denmark | Female | 2023-04-25 |
| NCT05797909 ClinicalTrials.gov |
The PCOS Challenge Study | PCOS Challenge: The National Polycystic Ovary Syndrome Association | Observational | Recruiting | 2022-06-22 | 2042-06 (est.) | 15,000 | United States | Female | 2023-04-04 |
| NCT01601171 ClinicalTrials.gov |
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate | Centre Hospitalier Universitaire Vaudois | Observational | Recruiting | 2012-03 | 2025-03 (est.) | 2,000 | Switzerland | All | 2022-06-21 |
| NCT05177562 ClinicalTrials.gov |
Reproductive Endocrinology Oxford Study (RepOx) | University of Oxford | Observational | Recruiting | 2021-10-21 | 2028-09-01 (est.) | 1,175 | United Kingdom | Female | 2022-01-04 |
| NCT03585738 ClinicalTrials.gov |
Effects of Oral Inositol Supplementation on Obstetrics Outcomes in PCOS Women | Università degli Studi dell'Insubria | N/A (non-drug) | Not yet recruiting | 2022-01-01 (est.) | 2024-12-31 (est.) | 80 | — | Female | 2020-11-05 |
| NCT04149496 ClinicalTrials.gov |
IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer | Bruce Rose, MD | N/A (non-drug) | Recruiting | 2019-05-10 | 2023-04-01 (est.) | 300 | United States | Female | 2019-11-04 |
| NCT03991507 ClinicalTrials.gov |
PCOS (Polycystic Ovarian Syndrome) Patients | The First Affiliated Hospital of Zhengzhou University | Observational | Recruiting | 2010-01-01 | 2050-12-31 (est.) | 10,000 | China | Female | 2019-06-19 |
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One short email a week on PCOS trials: new registrations, status changes, results postings and sponsor moves, each with registry links.
- US and EU registries merged and de-noised
- Plain-English one-line summary per change
- Also tracked: Endometriosis trials · Menopause trials. More coming: fibroids, fertility, maternal health, female cancers
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Coming next: women-representation scoring Preview · not live
Representation scoring isn't meaningful for PCOS, because nearly all of these trials enrol only women. On mixed-sex trials (heart disease, oncology, neurology and so on), TrialsForHer will compare the share of women enrolled against the share of women living with the condition. That is the participation-to-prevalence ratio used in FDA and academic analyses. It will also flag trials that don't report results by sex. Scores will come only from registry-reported baseline data, with links to the source, and no scores are shown on this page.
Methodology
- US: ClinicalTrials.gov API v2, condition search
polycystic ovary syndrome OR PCOS(1,118 records in total). Listed here: recruiting or not yet recruiting (138), plus any record updated or first posting results in the last 90 days. - EU: CTIS public search API, full-text and medical-condition searches for the same terms (9 trials; CTIS covers EU trials submitted under the Clinical Trials Regulation since 2023). Listed here: authorised or ongoing and recruiting (6), plus any record updated in the last 90 days. Off-topic matches are removed with a keyword check on each record's conditions and title (38 removed this run).
- "Updated" means the registry's last-update date. It can be any change, from a new site to a status change.
- Phases are grouped across both registries (for example, CTIS "Therapeutic exploratory (Phase II)" → Phase 2). "N/A" means a device, procedure or behavioural study.
- Site share counts open trials with at least one site in the US or the EU-27. A multinational trial can count in both.
- Fields are shown as the registry records them, and "(est.)" marks the sponsor's estimated dates. A trial registered in both systems may appear twice.
- Data pulled 21 Oct 2026, 10:06 UTC and regenerated automatically.
Sources
- ClinicalTrials.gov API v2, U.S. National Library of Medicine
- EU Clinical Trials Information System (CTIS), European Medicines Agency
Disclaimer
Business research data, not medical advice. TrialsForHer summarises public registry records for professional and research use. It isn't medical advice, doesn't recommend or endorse any trial or treatment, and isn't a way to enrol in a study. Registry entries can be incomplete or out of date, so always check the official record. If you're a patient or carer, talk to your clinician or contact the study team listed on the registry.